Biochemical characterisation of a kunitz-type inhibitor from tamarindus indica L. seeds and its efficacy in reducing plasma leptin in an experimental model of obesity

A trypsin inhibitor isolated from tamarind seed (TTI) has satietogenic effects in animals, increasing the cholecystokinin (CCK) in eutrophy and reducing leptin in obesity. We purified TTI (pTTI), characterised, and observed its effect upon CCK and leptin in obese Wistar rats. By HPLC, and after ampl...

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Detalhes bibliográficos
Principais autores: Maciel, Bruna Leal Lima, Medeiros, Amanda Fernandes de, Costa, Izael de Sousa, Carvalho, Fabiana Maria Coimbra de, Kiyota, Sumika, Souza, Beatriz Blenda Pinheiro de, Sifuentes, Daniel Nogoceke, Serquiz, Raphael Paschoal, Uchôa, Adriana Ferreira, Santos, Elizeu Antunes dos, Morais, Ana Heloneida de Araújo
Formato: article
Idioma:English
Publicado em: Journal of Enzyme Inhibition and Medicinal Chemistry
Assuntos:
Tamarind
Antitryptic
Wistar rats
CCK
Endereço do item:https://repositorio.ufrn.br/handle/123456789/57470
http://dx.doi.org/10.1080/14756366.2017.1419220
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https://repositorio.ufrn.br/handle/123456789/57470
http://dx.doi.org/10.1080/14756366.2017.1419220

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