An insulin receptor-binding multifunctional protein from tamarindus indica L. presents a hypoglycemic effect in a diet-induced type 2 diabetes-preclinical study

The objectives of this study were to evaluate the hypoglycemic effect of the trypsin inhibitor isolated from tamarind seeds (TTI) in an experimental model of T2DM and the in silico interaction between the conformational models of TTI 56/287 and the insulin receptor (IR). After inducing T2DM, 15 male...

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Detalhes bibliográficos
Principais autores: Maciel, Bruna Leal Lima, Costa, Izael de Sousa, Lima, Mayara Santos Rosa, Medeiros, Amanda, Bezerra, Lucas Lima, Santos, Paula, Serquiz, Alexandre, Lima, Maíra Conceição Jerônimo de Souza, Oliveira, Gerciane Santos de, Santos, Elizeu Antunes dos, Monteiro, Norberto de Kássio Vieira, Morais, Ana Heloneida
Formato: article
Idioma:English
Publicado em: Foods
Assuntos:
Trypsin inhibitor
Tamarind
Hypoglycemic agent
Plant proteins
Molecular docking simulation
Endereço do item:https://repositorio.ufrn.br/handle/123456789/57445
http://dx.doi.org/10.3390/foods11152207
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https://repositorio.ufrn.br/handle/123456789/57445
http://dx.doi.org/10.3390/foods11152207

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