Entry of cholera toxin into polarized human intestinal epithelial cells. Identification of an early brefeldin a sensitive event required for A1-peptide generation

The effect of brefeldin-A (BFA), a reversible inhibitor of vesicular transport, on cholera toxin (CT)-induced Cl- secretion (Isc) was examined in the polarized human intestinal cell line, T84. Pretreatment of T84 monolayers with 5 microM BFA reversibly inhibited Isc in response to apical or basolate...

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Principais autores: Almeida, Jose Bruno de, Lencer, W. I., Moe, S., Stow, Jennifer L., Ausiello, Dennis A., Madara, J. L.
Formato: article
Idioma:pt_BR
Publicado em: American Society for Clinical Investigation
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Endereço do item:https://repositorio.ufrn.br/handle/123456789/54382
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