Coexpression of p53 protein and MDR functional phenotype in leukemias: the predominant association in chronic myeloid leukemia
Background: One of the best characterized resistance mechanisms of leukemias is multidrug resistance (MDR) mediated by P-glycoprotein (Pgp) and multidrug-resistant related protein (MRP). In addition to Pgp and MRP, p53 mutation or inactivation might play a relevant role in therapeutic failure. Some...
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| Principais autores: | , , , , , , |
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| Formato: | article |
| Idioma: | English |
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Wiley
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| Endereço do item: | https://repositorio.ufrn.br/handle/123456789/51006 |
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