Long-term potentiation prevents ketamine-induced aberrant neurophysiological dynamics in the hippocampus-prefrontal cortex pathway in vivo
N-methyl-D-aspartate receptor (NMDAr) antagonists such as ketamine (KET) produce psychotic-like behavior in both humans and animal models. NMDAr hypofunction affects normal oscillatory dynamics and synaptic plasticity in key brain regions related to schizophrenia, particularly in the hippocampus and...
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Principais autores: | Lopes-Aguiar, Cleiton, Ruggiero, Rafael N., Rossignoli, Matheus T., Esteves, Ingrid de Miranda, Peixoto-Santos, José Eduardo, Romcy-Pereira, Rodrigo Neves, Leite, João P. |
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Formato: | article |
Idioma: | English |
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Endereço do item: | https://repositorio.ufrn.br/jspui/handle/123456789/28835 https://doi.org/10.1038/s41598-020-63979-5 |
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