Essential Saccharomyces cerevisiae genome instability suppressing genes identify potential human tumor suppressors

Gross Chromosomal Rearrangements (GCRs) play an important role in human diseases, including cancer. Although most of the nonessential Genome Instability Suppressing (GIS) genes in Saccharomyces cerevisiae are known, the essential genes in which mutations can cause increased GCR rates are not well un...

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Principais autores: Srivatsan, Anjana, Li, Binzhong, Sanchez, Dafne N., Somach, Steven B., Silva, Vandeclecio L. da, Souza, Sandro José de, Putnam, Christopher D., Kolodner, Richard D.
Formato: article
Idioma:English
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Assuntos:
Genome instability
chromosome dynamics and replication
cancer
Endereço do item:https://repositorio.ufrn.br/jspui/handle/123456789/27645
https://doi.org/10.1073/pnas.1906921116
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https://repositorio.ufrn.br/jspui/handle/123456789/27645
https://doi.org/10.1073/pnas.1906921116

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