Influence of BRCA1 germline mutations in the somatic mutational burden of triple-negative breast cancer
The majority of the hereditary triple-negative breast cancers (TNBCs) are associated with BRCA1 germline mutations. Nevertheless, the understanding of the role of BRCA1 deficiency in the TNBC tumorigenesis is poor. In this sense, we performed whole-exome sequencing of triplet samples (leucocyte, tum...
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| Principais autores: | , , , , , , , |
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| Formato: | article |
| Idioma: | English |
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| Endereço do item: | https://repositorio.ufrn.br/jspui/handle/123456789/27644 |
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