Activity Cliff como ferramenta na análise da relação estrutura atividade em uma série de inibidores da enzima FabH bacteriana

The synthesis of fatty acids, mainly by the enzyme β-ketoacyl-ACP synthase III (FabH), has been emerging as an excellent target for new molecules with antimicrobial action. Despite the urgency generated by increasing bacterial resistance, the synthesis of new molecules is a very expensive task in...

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Bibliographische Detailangaben
1. Verfasser: Santos, Rodolfo André de Araújo
Weitere Verfasser: Barbosa, Euzebio Guimarães
Format: Dissertação
Sprache:pt_BR
Veröffentlicht: Brasil
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Online Zugang:https://repositorio.ufrn.br/jspui/handle/123456789/26845
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