Complex landscape of germline variants in brazilian patients with hereditary and early onset breast cancer
Pathogenic variants in known breast cancer (BC) predisposing genes explain only about 30% of Hereditary Breast Cancer (HBC) cases, whereas the underlying genetic factors for most families remain unknown. Here, we used whole-exome sequencing (WES) to identify genetic variants associated to HBC in 17...
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Principais autores: | , , , , , , , , , , , , , , , |
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Formato: | article |
Idioma: | eng |
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Endereço do item: | https://doi.org/10.3389/fgene.2018.00161 https://repositorio.ufrn.br/jspui/handle/123456789/25458 |
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