Direct reprogramming of adult human somatic stem cells into functional neurons using Sox2, Ascl1, and Neurog2

Reprogramming of somatic cells into induced pluripotent stem cells (iPS) or directly into cells from a different lineage, including neurons, has revolutionized research in regenerative medicine in recent years. Mesenchymal stem cells are good candidates for lineage reprogramming and autologous trans...

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Principais autores: Araújo, Jessica Alves de Medeiros, Hilscher, Markus M., Marques-Coelho, Diego, Golbert, Daiane C. F., Cornelio, Deborah A., Medeiros, Silvia R. Batistuzzo de, Leão, Richardson Naves, Costa, Marcos Romualdo
Formato: article
Idioma:eng
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Assuntos:
induced neurons
lineage reprogramming
human mesenchymal stem cells
umbilical cord
proneural genes
Endereço do item:https://repositorio.ufrn.br/jspui/handle/123456789/25457
https://doi.org/10.3389/fncel.2018.00155
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https://repositorio.ufrn.br/jspui/handle/123456789/25457
https://doi.org/10.3389/fncel.2018.00155

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