Carvedilol Improves Inflammatory Response, Oxidative Stress and Fibrosis in the Alcohol-Induced Liver Injury in Rats by Regulating Kuppfer Cells and Hepatic Stellate Cells
Aim To evaluate the anti-inflammatory, anti-oxidant and antifibrotic effects of carvedilol (CARV) in rats with ethanol-induced liver injury. Methods Liver injury was induced by gavage administration of alcohol (7 g/kg) for 28 consecutive days. Eighty Wistar rats were pretreated with oral CARV at...
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| Principais autores: | , , , , , , |
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| Formato: | article |
| Idioma: | eng |
| Publicado em: |
University of Navarra School of Medicine and Center for Applied Medical Research (CIMA), SPAIN
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| Assuntos: | |
| Endereço do item: | https://repositorio.ufrn.br/jspui/handle/123456789/25434 https://doi.org/10.1371/journal.pone.0148868 |
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