Seizures triggered by pentylenetetrazol in marmosets made chronically epileptic with pilocarpine show greater refractoriness to treatment
The efficiency of most of the new antiepileptic drugs (AEDs) on clinical trials still falls short the success reported in pre-clinical studies, possibly because the validity of the animal models is insufficient to fully represent the human pathology. To improve the translational value for testing AE...
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Principais autores: | , , , , , |
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Formato: | article |
Idioma: | eng |
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Endereço do item: | https://repositorio.ufrn.br/jspui/handle/123456789/23353 http://dx.doi.org/10.1016/j.eplepsyres.2016.06.012 |
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