Testing for Natural Selection in Human Exonic Splicing Regulators Associated with Evolutionary Rate Shifts

Despite evidence that at the interspecific scale, exonic splicing silencers (ESSs) are under negative selection in constitutive exons, little is known about the effects of slightly deleterious polymorphisms on these splicing regulators. Through the application of a modified version of the McDon...

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Principais autores: Ramalho, Rodrigo F., Gelfman, Sahar, Souza, Jorge E. de, Ast, Gil, Souza, Sandro José de, Meyer, Diogo
Formato: article
Idioma:eng
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Endereço do item:https://repositorio.ufrn.br/jspui/handle/123456789/23332
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