Minocycline treatment reduces white matter damage after excitotoxic striatal injury

We investigated the protective effects of minocycline following white matter damage (WMD) in the rat striatum. Excitotoxic lesions were induced by N-Methyl-D-Aspartate (NMDA) microinjections and caused striatal damage, concomitant with microglial/ macrophage activation. The excitotoxic lesion bot...

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Principais autores: Guimarães, Joanilson S., Freire, Marco Aurelio M., Lima, Rafael R., Picanço-Diniz, Cristovam W., Pereira, Antonio, Gomes-Leal, Walace
Format: article
Jezik:eng
Izdano:
Teme:
Excitotoxicity
Neurodegeneration
Oligodendrocyte
Myelin
White matter
Striatum
Online dostop:https://repositorio.ufrn.br/jspui/handle/123456789/23119
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https://repositorio.ufrn.br/jspui/handle/123456789/23119

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