A genomic case study of desmoplastic small round cell tumor: comprehensive analysis reveals insights into potential therapeutic targets and development of a monitoring tool for a rare and aggressive disease

Background: Genome-wide profiling of rare tumors is crucial for improvement of diagnosis, treatment, and, consequently, achieving better outcomes. Desmoplastic small round cell tumor (DSRCT) is a rare type of sarcoma arising from mesenchymal cells of abdominal peritoneum that usually develops in mal...

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Principais autores: Ferreira, Elisa Napolitano, Barros, Bruna Durães Figueiredo, Souza, Jorge Estefano de, Almeida, Renan Valieris, Torrezan, Giovana Tardin, Garcia, Sheila, Krepischi, Ana Cristina Victorino, Mello, Celso Abdon Lopes de, Cunha, Isabela Werneck da, Pinto, Clóvis Antonio Lopes, Soares, Fernando Augusto, Dias-Neto, Emmanuel, Lopes, Ademar, Souza, Sandro José de, Carraro, Dirce Maria
Formato: article
Idioma:eng
Publicado em:
Assuntos:
Desmoplastic small round cell tumor
Genomic profiling
Whole-exome sequencing
EWS-WT1 gene fusion
Personalized biomarker
Liquid biopsy
Endereço do item:https://repositorio.ufrn.br/jspui/handle/123456789/23051
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https://repositorio.ufrn.br/jspui/handle/123456789/23051

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