Isolamento e identificação de Streptococcus agalactiae em mulheres cisgênero grávidas

Streptococcus agalactiae (GBS) is a gram-positive cocci, which have the gastrointestinal tract as their reservoir, but can colonize the genitourinary tract. In pregnant cisgender women, they can be asymptomatically or, as a urinary infection, can compromise the progress of the pregnancy. The g...

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Autor principal: Silva, Rosiane Maria da
Outros Autores: Nascimento, Ermeton Duarte do
Formato: bachelorThesis
Idioma:pt_BR
Publicado em: Universidade Federal do Rio Grande do Norte
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Endereço do item:https://repositorio.ufrn.br/handle/123456789/57771
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Resumo:Streptococcus agalactiae (GBS) is a gram-positive cocci, which have the gastrointestinal tract as their reservoir, but can colonize the genitourinary tract. In pregnant cisgender women, they can be asymptomatically or, as a urinary infection, can compromise the progress of the pregnancy. The great medical relevance of this microorganism lies in the possibility of it being vertically transmitted to newborns and causing them complications, such as sepsis, pneumonia and meningitis. The objective of this work was to carry out a literature review of scientific articles based on the isolation and identification of Streptococcus agalactiae in Brazilian pregnant cisgender women in the last 10 years. The methodology used was a bibliographic review of articles found in the SciELO, PubMed and BIREME databases, using the descriptors “Streptococcus agalactiae”, “pregnant women” and “genito-urinary infection”, in Portuguese, English and Spanish, and then applied inclusion and exclusion criteria. Result: 20 articles were found that fit the research, for which it was observed that the majority used identification and isolation methods for women from 35 to 37 weeks of gestation, through microbial culture, but there were cases that were used PCR. Prevalence data varied, but the vast majority were within the Brazilian average (4.6 to 35,6%). The most common clinical complications found in women infected with GBS were Diabetes Mellitus, high blood pressure and urinary infection. And regarding bacterial resistance, although clindamycin and erythromycin were the most cited drugs, it was observed that the highest resistance rates were found for tetracycline.