Contaminantes emergentes: uma abordagem ecológica, sanitária e social da poluição por fármacos

Among the numerous compounds that are considered emerging pollutants, drugs gained prominence, as they began to be detected in small concentrations in different environmental matrices. These substances are widely used in veterinary and human medicine. In the context of the COVID-19 pandemic, ther...

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Autor principal: Costa, Rafaela dos Santos
Outros Autores: Navoni, Júlio Alejandro
Formato: doctoralThesis
Idioma:pt_BR
Publicado em: Universidade Federal do Rio Grande do Norte
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Endereço do item:https://repositorio.ufrn.br/handle/123456789/53570
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Resumo:Among the numerous compounds that are considered emerging pollutants, drugs gained prominence, as they began to be detected in small concentrations in different environmental matrices. These substances are widely used in veterinary and human medicine. In the context of the COVID-19 pandemic, there was an increase in the consumption of these compounds and, consequently, in the environmental and health impacts. These contaminants can be introduced into the environment by different routes. Given this scenario, it is essential to understand the consequences of drugs on different organisms, as well as the causes that lead to their occurrence at an environmental level. Thus, the present study aimed to evaluate the effects of pharmaceutical products on cyanobacteria as an ecological and sanitary representation of this problem, in addition to analyzing the perception and habits of the Brazilian population regarding this environmental issue, as well as investigating the quality and means of dissemination of scientific information on this topic. Additionally, the object of study is used as a means of contextualizing the environmental injustices observed in Brazil. The first chapter of this thesis aimed to describe the effects and risks of these compounds in the environment, having cyanobacteria as a representative, due to their role as primary producers and implications for human health. It was evidenced that different therapeutic classes, depending on the tested concentrations, can affect its physiology, as well as the potential effects on public health, due to the production of cyanotoxins. In addition, to understand the consequences at an ecological level, it is necessary to understand the causes that favor the incorporation of drugs into the environment. Thus, the second chapter aimed to describe how the Brazilian population perceives and acts in relation to the life cycle of drugs from an environmental perspective through a study carried out online. The results showed that the main way to dispose of medicines for human and veterinary use is common waste. The information obtained also revealed the self-medication habit of the interviewees and that the most consumed therapeutic classes of drugs could be associated with the COVID-19 pandemic situation, the period in which the research was conducted. The work also highlighted the incipient implementation of reverse logistics laws and the need to understand how the theme of emerging contaminants is reaching society. Therefore, the third chapter of the thesis aimed to investigate, through an analysis of Brazilian scientific dissemination sites, how scientific information was conveyed and its quality considering the lay public as the final recipient. The results obtained showed limitations in the dissemination process to the detriment of the current speed of content sharing. Therefore, it is emphasized that education is essential for the reader to have a solid foundation that allows the identification and quality of the information disclosed, establishing a critical view on issues of environmental relevance, such as those involving the theme of emerging contaminants. There was also a lack of texts aimed at children and youth, which are fundamental pillars for building a sustainable future. As a result, the fourth chapter of the thesis consists of two scientific dissemination articles for children on topics covered in this research, as a way to remedy one of the previously found gaps. Finally, and aiming at the findings obtained in the course of this research, the problem of drug contamination was fully addressed from the perspective of environmental justice and used as a representation of social inequalities already observed in the Brazilian context. The critical review raised issues such as lack of basic sanitation, educational quality, lack of inspection and/or implementation of environmental legislation, food insecurity, and public health in a segregationist, ethnic-racial context, with mainly ideological implications, associated with pollution by these substances, and aggravated by the COVID-19 pandemic condition. The historical issue of social inequalities in Brazil is reaffirmed by the occurrence of drugs in the environment and their implications for marginalized and susceptible social groups. In view of the above, it is clear that drug contamination needs to be understood from a transdisciplinary perspective on its effects on the environment, going through legal issues in environmental issues and including the social sphere not only as waste generators but also as vulnerable beings of the own consequences of their acts, aggravated especially by the lack of environmental education at all educational levels as well as other factors of socio-environmental inequalities already observed.