Fatores associados ao status de vitamina E de puérperas: uma revisão sistemática
Introduction: Vitamin E, also known as alpha-tocopherol, is a potent antioxidant. Maternal nutritional status of alpha-tocopherol is directly associated with fetal and newborn serum levels. In this context, its lack may imply a risk of damage to maternal and child health, which will be predisp...
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| Formato: | bachelorThesis |
| Idioma: | pt_BR |
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Universidade Federal do Rio Grande do Norte
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| Endereço do item: | https://repositorio.ufrn.br/handle/123456789/53291 |
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| Resumo: | Introduction: Vitamin E, also known as alpha-tocopherol, is a potent antioxidant. Maternal
nutritional status of alpha-tocopherol is directly associated with fetal and newborn serum
levels. In this context, its lack may imply a risk of damage to maternal and child health, which
will be predisposed to greater oxidative stress. Objectives: To systematize information on
factors that may be associated with maternal vitamin E status, aiming to find possible
interconnections between the occurrence of specific situations and vitamin deficiency in the
puerperium. Methodology: This protocol is registered in the International Prospective Register
of Systematic Reviews (PROSPERO) (CDR 42022335788) and followed the
recommendations of the Preferred Reporting Items for Systematic Review and Meta-Analysis
Protocols (PRISMA-P). The search was performed in the following databases: PubMed/
MEDLINE, SCOPUS, EMBASE, Web of Science, VHL and SciELO. Based on the eligibility
criteria previously defined in the review, we included articles of the observational type, which
brought serum vitamin E status of puerperal women and associated factors, and those that did
not meet the inclusion criteria were excluded. Two independent reviewers performed the steps
of the systematic review. The methodological quality was analyzed by the Newcastle–Ottawa
(NOS) and Joanna Briggs Institute (JBI) scale and the critical analysis of the selected studies
was done using Microsoft Office Excel®. Results: The search resulted in 107 articles found,
of which only 12 were eligible. The sample size in the reviewed studies ranged from 27 to 429
postpartum women, with a high degree of variability regarding associated factors. The
existence of current or previous comorbidities in postpartum women such as preeclampsia,
gestational diabetes mellitus and human immunodeficiency virus (HIV); maternal
socioeconomic conditions; smoking; the gestational age at birth of the baby; the type of
delivery; the existence of throughout pregnancy, as well as post-gestational metabolic changes
such as lipid peroxidation, may be intrinsically linked to maternal serum vitamin E levels.
There are associated factors that can directly influence the status of vitamin E, and their
knowledge is important to avoid possible damage to maternal and child health. But still, there
is a need for more studies on the subject. |
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