Progressive encephalopathy due to chronic exposure to lead

A 70-year-old man reported a 2-year history of progressive gait imbalance and cognitive decline (memory, executive functions, and language impairment). A physical examination revealed spastic ataxia without peripheral involvement. The patient worked with car battery solutions for 40 years, until 13...

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Principais autores: Brito, Paulo Santiago de Morais, Aquino, Bárbara Cristina Vieira de, Pessoa Neto, Agábio Diógenes, Freire, Mariana Galvão de Lima Martins, Fidelix, Emanuela Coriolano, Moreira Neto, Manuel, Silva, Rodrigo Alencar e, Godeiro Junior, Clécio de Oliveira
Outros Autores: https://orcid.org/0000-0002-0010-7217
Formato: article
Idioma:English
Publicado em: Arquivos de Neuro-Psiquiatria
Assuntos:
encephalopathy
progressive gait imbalance
cognitive decline
Endereço do item:https://repositorio.ufrn.br/handle/123456789/53222
http://dx.doi.org/10.1055/s-0042-1758393
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spelling ri-123456789-532222023-07-11T16:15:36Z Progressive encephalopathy due to chronic exposure to lead Encefalopatia progressiva por exposição crônica ao chumbo Brito, Paulo Santiago de Morais Aquino, Bárbara Cristina Vieira de Pessoa Neto, Agábio Diógenes Freire, Mariana Galvão de Lima Martins Fidelix, Emanuela Coriolano Moreira Neto, Manuel Silva, Rodrigo Alencar e Godeiro Junior, Clécio de Oliveira https://orcid.org/0000-0002-0010-7217 encephalopathy progressive gait imbalance cognitive decline A 70-year-old man reported a 2-year history of progressive gait imbalance and cognitive decline (memory, executive functions, and language impairment). A physical examination revealed spastic ataxia without peripheral involvement. The patient worked with car battery solutions for 40 years, until 13 years ago.1 He had several hospitalizations due to acute lead poisoning, with levels of lead in the blood and urinary delta-aminolevulinic acid of 162,8 g/dl and 20 mg/U (normal: up to 40 g/dl and 4,5 mg/U) respectively). Recent brain neuroimages showed typical findings of saturnism,2 with normal bone profile blood tests. Therefore, chronic lead poisoning should be remembered as an environmental cause of leukoencephalopathy. 2023-07-11T16:15:10Z 2023-07-11T16:15:10Z 2022 article AQUINO, Bárbara Cristina Vieira de; PESSOA NETO, Agábio Diógenes; FREIRE, Mariana Galvão de Lima Martins; FIDELIX, Emanuela Coriolano; BRITO, Paulo Santiago de Morais; MOREIRA NETO, Manuel; SILVA, Rodrigo Alencar e; GODEIRO JUNIOR, Clécio de Oliveira. Progressive encephalopathy due to chronic exposure to lead. Arquivos de Neuro-Psiquiatria, [S.L.], v. 80, n. 10, p. 1079-1080, out. 2022. Georg Thieme Verlag KG. http://dx.doi.org/10.1055/s-0042-1758393. Disponível em: https://www.thieme-connect.de/products/ejournals/html/10.1055/s-0042-1758393. Acesso em: 10 jul. 2023. https://repositorio.ufrn.br/handle/123456789/53222 http://dx.doi.org/10.1055/s-0042-1758393 en Attribution 3.0 Brazil http://creativecommons.org/licenses/by/3.0/br/ application/pdf Arquivos de Neuro-Psiquiatria
institution Repositório Institucional
collection RI - UFRN
language English
topic encephalopathy
progressive gait imbalance
cognitive decline
spellingShingle encephalopathy
progressive gait imbalance
cognitive decline
Brito, Paulo Santiago de Morais
Aquino, Bárbara Cristina Vieira de
Pessoa Neto, Agábio Diógenes
Freire, Mariana Galvão de Lima Martins
Fidelix, Emanuela Coriolano
Moreira Neto, Manuel
Silva, Rodrigo Alencar e
Godeiro Junior, Clécio de Oliveira
Progressive encephalopathy due to chronic exposure to lead
description A 70-year-old man reported a 2-year history of progressive gait imbalance and cognitive decline (memory, executive functions, and language impairment). A physical examination revealed spastic ataxia without peripheral involvement. The patient worked with car battery solutions for 40 years, until 13 years ago.1 He had several hospitalizations due to acute lead poisoning, with levels of lead in the blood and urinary delta-aminolevulinic acid of 162,8 g/dl and 20 mg/U (normal: up to 40 g/dl and 4,5 mg/U) respectively). Recent brain neuroimages showed typical findings of saturnism,2 with normal bone profile blood tests. Therefore, chronic lead poisoning should be remembered as an environmental cause of leukoencephalopathy.
author2 https://orcid.org/0000-0002-0010-7217
author_facet https://orcid.org/0000-0002-0010-7217
Brito, Paulo Santiago de Morais
Aquino, Bárbara Cristina Vieira de
Pessoa Neto, Agábio Diógenes
Freire, Mariana Galvão de Lima Martins
Fidelix, Emanuela Coriolano
Moreira Neto, Manuel
Silva, Rodrigo Alencar e
Godeiro Junior, Clécio de Oliveira
format article
author Brito, Paulo Santiago de Morais
Aquino, Bárbara Cristina Vieira de
Pessoa Neto, Agábio Diógenes
Freire, Mariana Galvão de Lima Martins
Fidelix, Emanuela Coriolano
Moreira Neto, Manuel
Silva, Rodrigo Alencar e
Godeiro Junior, Clécio de Oliveira
author_sort Brito, Paulo Santiago de Morais
title Progressive encephalopathy due to chronic exposure to lead
title_short Progressive encephalopathy due to chronic exposure to lead
title_full Progressive encephalopathy due to chronic exposure to lead
title_fullStr Progressive encephalopathy due to chronic exposure to lead
title_full_unstemmed Progressive encephalopathy due to chronic exposure to lead
title_sort progressive encephalopathy due to chronic exposure to lead
publisher Arquivos de Neuro-Psiquiatria
publishDate 2023
url https://repositorio.ufrn.br/handle/123456789/53222
http://dx.doi.org/10.1055/s-0042-1758393
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