Eficácia clínica e indução de sensibilidade dos peróxidos de hidrogênio e carbamida no clareamento dentário de consultório: uma revisão sistemática

Objective: This systematic review aimed to answer the question: is carbamide peroxide as effective as hydrogen peroxide and causes less sensitivity to in-office bleaching? Materials and Methods: A literature search was performed on PubMed/Medline, Embase, Scopus, ISI Web of Science, and gray literat...

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Detalhes bibliográficos
Autor principal: Boa, Patrick Wesley Marques de
Outros Autores: Borges, Boniel Castillo Dutra
Formato: bachelorThesis
Idioma:pt_BR
Publicado em: Universidade Federal do Rio Grande do Norte
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Endereço do item:https://repositorio.ufrn.br/handle/123456789/52570
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Resumo:Objective: This systematic review aimed to answer the question: is carbamide peroxide as effective as hydrogen peroxide and causes less sensitivity to in-office bleaching? Materials and Methods: A literature search was performed on PubMed/Medline, Embase, Scopus, ISI Web of Science, and gray literature. Clinical trials comparing efficacy or in-office bleaching sensitivity with hydrogen peroxide and carbamide were included. Risk of bias and certainty of evidence were assessed, respectively, with the Risk of Bias 2.0 (RoB2) tool and the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach for efficacy (color change) and bleaching sensitivity. Results: three studies selected for qualitative analysis after database screening. Two studies evaluated bleaching sensitivity and, in these studies, low risk of bias prevailed. 37% Carbamide peroxide and 35% Hydrogen peroxide promoted similar efficacy for in-office bleaching in studies that used three bleaching sessions, with low certainty of evidence. 37% carbamide peroxide caused less bleaching sensitivity than 35% hydrogen peroxide, with moderate evidence certainty. Conclusion: Limited evidence suggests 37% carbamide peroxide as similarly effective to 35% hydrogen peroxide for in-office bleaching causing less sensitivity. However, well-designed, split-mouth clinical trials are suggested in order to strengthen the evidence. Clinical Relevance: Using 37% carbamide peroxide in three sessions promotes effective in-office whitening and generates less sensitivity for patients.