Desenvolvimento oocitário e embrionário de mulheres submetidas a tratamento de reprodução assistida e suas relações com a idade E, hábitos de vida materno e fator masculino
Infertility is a public health problem that affects many couples around the world. Numerous factors can change the quantity and quality of oocytes, as well the quality of the embryos produced in assisted human reproduction treatments, with emphasis on age and obesity in women, as well as the pres...
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| Formato: | bachelorThesis |
| Idioma: | pt_BR |
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Universidade Federal do Rio Grande do Norte
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| Endereço do item: | https://repositorio.ufrn.br/handle/123456789/50900 |
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| Resumo: | Infertility is a public health problem that affects many couples around the world.
Numerous factors can change the quantity and quality of oocytes, as well the quality
of the embryos produced in assisted human reproduction treatments, with emphasis
on age and obesity in women, as well as the presence of infertility in men. Therefore,
the aimed of this study was to carry out a descriptive, cross-sectional and retrospective
observational analysis of the relationship between the oocyte and embryonic
development of patients undergoing assisted reproduction treatment at the Assisted
Reproduction Center of the Januário Cicco Maternity School (CRA/MEJC), Natal/ RN,
between 2013 and 2018, with female age and life habits, as well with male factor of
infertility. Regarding the age of the patients, significant correlations were found with
the number of oocytes captured, mature and blastocysts. For the body mass index
(BMI), the correlations were significative for the number of oocytes discarded and the
cleavage rate. Together, age and BMI were statistically significant in predicting the
number of grade 1 oocytes (germinal vesicle) and blastocysts. Regarding the
presence of the male factor and its influence on embryonic development, significant
differences were found in the number of blastocysts and positive beta-HCG indices.
The results of this study suggest that a woman's age and lifestyle can negatively affect
female fertility, compromising oocyte and embryonic development. When male factor
of infertility is present, embryonic development is affected, reflecting a smaller number
of embryos that reach the blastocyst stage and, consequently, lower levels of positive
beta-HCG. |
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