Análise Multiparamétrica da Pressão Inspiratória Nasal (SNIP) em indivíduos pós COVID-19
Introduction: Coronavirus (COVID-19) is an infectious disease caused by the SARS-CoV-2 virus that presents different clinical symptoms in individuals ranging from fever, cough, sore throat to dyspnea and muscle fatigue. The literature suggests that the respiratory muscles of post-COVID-19 patients m...
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| Formato: | bachelorThesis |
| Idioma: | pt_BR |
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Universidade Federal do Rio Grande do Norte
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| Endereço do item: | https://repositorio.ufrn.br/handle/123456789/50425 |
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| Resumo: | Introduction: Coronavirus (COVID-19) is an infectious disease caused by the SARS-CoV-2 virus that presents different clinical symptoms in individuals ranging from fever, cough, sore throat to dyspnea and muscle fatigue. The literature suggests that the respiratory muscles of post-COVID-19 patients may present important changes in their ability to generate force related to fatigue. To assess these changes, the PImax and PEmax measurement tests can be used, and in addition to these, in a complementary way, the SNIP can be performed to measure the inspiratory force when sniffing, to help identify predictors of fatigue in the respiratory muscles. Objective: To evaluate the variables of contraction and relaxation of the inspiratory muscles derived from the pressure curve of the SNIP test in patients with COVID-19 and compared to healthy subjects. Methodology: The sample consisted of two groups, one post-COVID-19 and a control group with healthy individuals who were recruited and evaluated in spirometry tests, maximal inspiratory and expiratory pressures, and SNIP. From the data generated by the SNIP curve, the relaxation rates of the inspiratory muscles were calculated, such as maximum relaxation rate (MRR) and half of the relaxation curve time (½ TR), in addition to the contraction properties of the same muscles, such as maximum rate of pressure development (MRPD) and contraction time (TC). Results: 29 post-COVID-19 subjects, with a mean age of 39.79 ± 13.36 years and 29 healthy subjects, with a mean age of 39.69 ± 12.42 years, were included. Post-COVID-19 individuals showed a statistically significant difference in respiratory muscle strength in SNIP (L) (p<0.0001) and SNIP (%pred.) (p<0.0001) values and in the related relaxation property at ½ TR (p<0.0001) compared to healthy individuals. Conclusion: The properties of contraction and relaxation of the respiratory muscles were altered by COVID-19, mainly in relation to its relaxation, both in individuals who were hospitalized or not. It is related to loss of muscle strength or associated fatigue. |
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