Biomarcadores urinários para detecção da endometriose: uma revisão integrativa
Endometriosis is a gynecological disease characterized by the presence and growth of endometrial-identical tissue outside the uterus, affecting about 10% of premenopausal women. With a variety of non-specific symptoms, in addition to the existence of asymptomatic patients, the diagnosis of endometri...
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| Formato: | bachelorThesis |
| Idioma: | pt_BR |
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Universidade Federal do Rio Grande do Norte
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| Endereço do item: | https://repositorio.ufrn.br/handle/123456789/50047 |
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| Resumo: | Endometriosis is a gynecological disease characterized by the presence and growth of endometrial-identical tissue outside the uterus, affecting about 10% of premenopausal women. With a variety of non-specific symptoms, in addition to the existence of asymptomatic patients, the diagnosis of endometriosis is challenging, which can delay its detection by up to 10 years and, therefore, delay the appropriate treatment, in addition to favoring the progression of the disease and the development of serious consequences such as tumors and infertility. This study aims to identify urinary biomarkers for early and less invasive diagnosis of endometriosis through an integrative literature review. Data collection was carried out from July to August 2022, using publications from the last 5 years found in the main databases (PubMed/MEDLINE, Portal de Periódicos Capes and SciELO), using descriptors with Boolean operators in the advanced search, as shown below: “Biomarkers” and “Endometriosis” and “Urine”. A total of 111 articles were found, but of these, only 10 articles were selected. In view of the results of the studies presented in this review, it is worth noting that most of the articles showed a positive correlation between the urinary biomarker studied and the presence of endometriosis, which could be used in the future as an alternative to improve the diagnosis, helping health professionals in the management of patients with endometriosis, in addition to mitigating the impact that this disease causes in the daily lives of patients and health services worldwide. |
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