Biological evaluations of nanocarriers to improve the effectiveness of colorectal cancer treatment
Nanotechnology is a promising tool for the treatment of cancer. In the past decades, major steps have been made to bring nanotechnology into the clinic in the form of nanoparticle-based drug delivery systems. The great hope of drug delivery systems is to reduce the side effects of chemotherapeuti...
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| Formato: | doctoralThesis |
| Idioma: | pt_BR |
| Publicado em: |
Universidade Federal do Rio Grande do Norte
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| Endereço do item: | https://repositorio.ufrn.br/handle/123456789/49871 |
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| Resumo: | Nanotechnology is a promising tool for the treatment of cancer. In the past decades,
major steps have been made to bring nanotechnology into the clinic in the form of
nanoparticle-based drug delivery systems. The great hope of drug delivery systems is to
reduce the side effects of chemotherapeutics while simultaneously increasing the
efficiency of the therapy. An increased treatment efficiency would greatly benefit the
quality of life as well as the life expectancy of cancer patients. However, besides its many
advantages, nanomedicines have to face several challenges and hurdles before they can be
used for the effective treatment of tumors. Here, we give an overview of the hallmarks of
cancer, especially colorectal cancer, and discuss biological barriers as well as how drug
delivery systems can be utilized for the effective treatment of tumors and metastases. |
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