Endodontia regenerativa: revisão integrativa

Endodontics is the branch of dentistry that studies the pulp and its periradicular tissues, with the aim of preventing, diagnosing and treating its various diseases. With the advance in the principles of regenerative endodontics, new protocols have emerged to regenerate and preserve the pulp tissue...

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Autor principal: Assis, Antônio Victor de Almeida
Outros Autores: Dametto, Fabio Roberto
Formato: bachelorThesis
Idioma:pt_BR
Publicado em: Universidade Federal do Rio Grande do Norte
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Endereço do item:https://repositorio.ufrn.br/handle/123456789/49085
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spelling ri-123456789-490852022-08-08T16:46:30Z Endodontia regenerativa: revisão integrativa Regenerative endodontics: integrative review Assis, Antônio Victor de Almeida Dametto, Fabio Roberto http://lattes.cnpq.br/7636313526704573 http://lattes.cnpq.br/3622339979189162 http://lattes.cnpq.br/1841520543955286 Faria Júnior, Norberto Batista de http://lattes.cnpq.br/1841520543955286 Carvalho, Rejane Andrade de http://lattes.cnpq.br/7060394224697599 Polpa dentária regeneração pulpar autotransplante cultivo celular endodontia regenerativa CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA::ENDODONTIA Endodontics is the branch of dentistry that studies the pulp and its periradicular tissues, with the aim of preventing, diagnosing and treating its various diseases. With the advance in the principles of regenerative endodontics, new protocols have emerged to regenerate and preserve the pulp tissue that was once lost. Among the various techniques studied in regenerative endodontics, we highlight cell therapy, a protocol that has been little studied in the literature. The aim of this review was to investigate the feasibility of pulp regeneration techniques using dental pulp stem cells, highlighting their advantages, disadvantages, clinical efficacy, indications and limitations. An integrative literature review was conducted by searching scientific articles in the electronic databases PubMed, Medline, Scopus and Web of science using the descriptors: pulp, regeneration, transplant, indexed in the period from 2017 to 2022. After the eligibility criteria, 14 studies were selected entirely in the English language. The studies showed the feasibility of cell culture techniques, as well as their excellent clinical results, with thickening of root walls, regression of lesions and positive response to sensitivity tests. However, the techniques have high financial, operational and laboratory costs for their development, and there is a lack of clinical trials to establish a clinical protocol. A endodontia é o ramo da odontologia que estuda a polpa e seus tecidos perirradiculares, com o intuito de prevenir, diagnosticar e tratar suas mais diversas doenças. Com o avanço nos princípios da endodontia regenerativa, novos protocolos surgiram a fim de regenerar e preservar o tecido pulpar outrora perdido. Dentre as diversas técnicas estudadas na endodontia regenerativa, dá-se destaque à terapia celular, protocolo há pouco estudado pela literatura. O objetivo desta revisão foi investigar a exequibilidade das técnicas de regeneração pulpar por meio de células tronco da polpa dentária, destacando suas vantagens, desvantagens, eficácia clínica, indicações e limitações. Uma revisão integrativa da literatura foi realizada por meio de uma busca de artigos científicos na base de dados eletrônica PubMed, Medline, Scopus e Web of science utilizando os descritores: pulp, regeneration, transplant, indexados no período de 2017 a 2022. Após os critérios de elegibilidade foram selecionados 14 estudos integralmente na língua inglesa. Os estudos mostraram a exequibilidade das técnicas de cultivo celular, assim como seus excelentes resultados clínicos, com espessamento das paredes radiculares, regressão de lesões e resposta positivas a testes de sensibilidade. Entretanto, as técnicas possuem altos custos financeiros, operacionais e laboratoriais para o seu desenvolvimento, além da falta de ensaios clínicos para confecção de um protocolo clínico. 2022-08-08T16:46:30Z 2022-08-08T16:46:30Z 2022-07-12 bachelorThesis ASSIS, Antônio Victor de Almeida. Endodontia regenerativa: revisão integrativa. 2022. 45f. Trabalho de Conclusão de Curso (Graduação em odontologia) - Departamento de odontologia, Universidade Federal do Rio Grande do Norte, Natal, 2022. https://repositorio.ufrn.br/handle/123456789/49085 pt_BR Attribution-NoDerivs 3.0 Brazil http://creativecommons.org/licenses/by-nd/3.0/br/ application/pdf Universidade Federal do Rio Grande do Norte Brasil UFRN Odontologia Departamento de Odontologia
institution Repositório Institucional
collection RI - UFRN
language pt_BR
topic Polpa dentária
regeneração pulpar
autotransplante
cultivo celular
endodontia regenerativa
CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA::ENDODONTIA
spellingShingle Polpa dentária
regeneração pulpar
autotransplante
cultivo celular
endodontia regenerativa
CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA::ENDODONTIA
Assis, Antônio Victor de Almeida
Endodontia regenerativa: revisão integrativa
description Endodontics is the branch of dentistry that studies the pulp and its periradicular tissues, with the aim of preventing, diagnosing and treating its various diseases. With the advance in the principles of regenerative endodontics, new protocols have emerged to regenerate and preserve the pulp tissue that was once lost. Among the various techniques studied in regenerative endodontics, we highlight cell therapy, a protocol that has been little studied in the literature. The aim of this review was to investigate the feasibility of pulp regeneration techniques using dental pulp stem cells, highlighting their advantages, disadvantages, clinical efficacy, indications and limitations. An integrative literature review was conducted by searching scientific articles in the electronic databases PubMed, Medline, Scopus and Web of science using the descriptors: pulp, regeneration, transplant, indexed in the period from 2017 to 2022. After the eligibility criteria, 14 studies were selected entirely in the English language. The studies showed the feasibility of cell culture techniques, as well as their excellent clinical results, with thickening of root walls, regression of lesions and positive response to sensitivity tests. However, the techniques have high financial, operational and laboratory costs for their development, and there is a lack of clinical trials to establish a clinical protocol.
author2 Dametto, Fabio Roberto
author_facet Dametto, Fabio Roberto
Assis, Antônio Victor de Almeida
format bachelorThesis
author Assis, Antônio Victor de Almeida
author_sort Assis, Antônio Victor de Almeida
title Endodontia regenerativa: revisão integrativa
title_short Endodontia regenerativa: revisão integrativa
title_full Endodontia regenerativa: revisão integrativa
title_fullStr Endodontia regenerativa: revisão integrativa
title_full_unstemmed Endodontia regenerativa: revisão integrativa
title_sort endodontia regenerativa: revisão integrativa
publisher Universidade Federal do Rio Grande do Norte
publishDate 2022
url https://repositorio.ufrn.br/handle/123456789/49085
work_keys_str_mv AT assisantoniovictordealmeida endodontiaregenerativarevisaointegrativa
AT assisantoniovictordealmeida regenerativeendodonticsintegrativereview
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