Lactobacillus rhamnosus interferes with candida albicans adherence and biofilm formation: a potential alternative treatment of candidiasis

The objective of the present study was to evaluate the ability of Lactobacillus rhamnosus, on different preparations (living lactobacilli, dead by heat lactobacilli and supernatant of lactobacilli suspension), to interfere with Candida albicans adherence to ephitelial cells and biofilm formation. Th...

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Detalhes bibliográficos
Principais autores: Ribeiro, F. C., Iglesias, M. C., Barros, Patrícia Pimentel de, Santos, S. S. F., Jorge, A. O. C., Leão, M. P. V.
Outros Autores: https://orcid.org/0000-0003-4885-2811
Formato: article
Idioma:English
Publicado em: Austin Publishing Group
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Endereço do item:https://repositorio.ufrn.br/handle/123456789/46767
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Resumo:The objective of the present study was to evaluate the ability of Lactobacillus rhamnosus, on different preparations (living lactobacilli, dead by heat lactobacilli and supernatant of lactobacilli suspension), to interfere with Candida albicans adherence to ephitelial cells and biofilm formation. The results showed a reduction of 66.2% in the number of Candida cells adhered to epithelial cells, when the suspension of living L. rhamnosus was used. On the same way, this suspension reduced the in vitro biofim formation by C. albicans. In conclusion, the suspension with living cells of L. rhamnosus was able to reduce the ability of C. albicans to adhere on ephitelial cells and to form biofilm, suggesting a potential use of this probiotic bacteria as a therapeutic agent in candidiasis