Antimicrobial activity from polymeric composites-based polydimethylsiloxane/TiO2/GO: evaluation of filler synthesis and surface morphology
Antimicrobial substances may be used to reduce hospital infections and inhibit food contamination, thus ensuring the safety and well being of humans. The objective of this study was to evaluate the antimicrobial activity of the polymeric nanocomposites polydimethylsiloxane (PDMS) embedded with tw...
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Principais autores: | , , , , , , , , , |
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Formato: | article |
Idioma: | English |
Publicado em: |
Springer
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Assuntos: | |
Endereço do item: | https://repositorio.ufrn.br/handle/123456789/44583 http://dx.doi.org/10.1007/s00289-016-1843-8 |
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Resumo: | Antimicrobial substances may be used to reduce hospital infections and
inhibit food contamination, thus ensuring the safety and well being of humans. The
objective of this study was to evaluate the antimicrobial activity of the polymeric
nanocomposites polydimethylsiloxane (PDMS) embedded with two types of fillers
based on titanium dioxide (commercial TiO2 P25 versus TiO2 via facile Micro-
wave-assisted hydrothermal-MAH synthesis) and graphene oxide (GO). The
nanocomposites were prepared using different compositions, concentrations, and
functionalizations (PDMS/TiO2/GO; PDMS/TiO2 and PDMS/GO). The antimicro-
bial activity of the samples was evaluated for different treatments on Candida
albicans, Staphylococcus aureus, and Enterococcus faecalis, by a modified direct
contact test (mDCT). The samples were also evaluated on surface morphology and
the roughness as a function of active particles insertion by atomic force microscopy
(AFM). Most of the PDMS films whose polymer was embedded with GO and
hydrothermal TiO2 showed the highest inhibition growth of bacteria and Candida
over 24 h. After 24 h, F, J, and H samples showed the best antibacterial activity,
whereas E showed the best antifungal activity. The results indicated that the
nanocomposites PDMS/GO/TiO2MAH and PDMS/GO sample enhanced antimi-
crobial activity in the treatments tested, therefore they were functional for con-
taminant reduction |
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