Antimicrobial activity from polymeric composites-based polydimethylsiloxane/TiO2/GO: evaluation of filler synthesis and surface morphology

Antimicrobial substances may be used to reduce hospital infections and inhibit food contamination, thus ensuring the safety and well being of humans. The objective of this study was to evaluate the antimicrobial activity of the polymeric nanocomposites polydimethylsiloxane (PDMS) embedded with tw...

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Detalhes bibliográficos
Principais autores: Correa, Camila F., Santana, Luiza R., Silva, Ricardo M., Noremberg, Bruno S., Lund, Rafael G., Ribeiro, Juliana S., Motta, Fabiana Villela da, Delmonte, Maurício Roberto Bomio, Nascimento, Rubens Maribondo do, Carreño, Neftalí Lênin Villarreal
Formato: article
Idioma:English
Publicado em: Springer
Assuntos:
Antimicrobial activity
Graphene oxide
Titanium dioxide
Polymer composite
Endereço do item:https://repositorio.ufrn.br/handle/123456789/44583
http://dx.doi.org/10.1007/s00289-016-1843-8
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Descrição
Resumo:Antimicrobial substances may be used to reduce hospital infections and inhibit food contamination, thus ensuring the safety and well being of humans. The objective of this study was to evaluate the antimicrobial activity of the polymeric nanocomposites polydimethylsiloxane (PDMS) embedded with two types of fillers based on titanium dioxide (commercial TiO2 P25 versus TiO2 via facile Micro- wave-assisted hydrothermal-MAH synthesis) and graphene oxide (GO). The nanocomposites were prepared using different compositions, concentrations, and functionalizations (PDMS/TiO2/GO; PDMS/TiO2 and PDMS/GO). The antimicro- bial activity of the samples was evaluated for different treatments on Candida albicans, Staphylococcus aureus, and Enterococcus faecalis, by a modified direct contact test (mDCT). The samples were also evaluated on surface morphology and the roughness as a function of active particles insertion by atomic force microscopy (AFM). Most of the PDMS films whose polymer was embedded with GO and hydrothermal TiO2 showed the highest inhibition growth of bacteria and Candida over 24 h. After 24 h, F, J, and H samples showed the best antibacterial activity, whereas E showed the best antifungal activity. The results indicated that the nanocomposites PDMS/GO/TiO2MAH and PDMS/GO sample enhanced antimi- crobial activity in the treatments tested, therefore they were functional for con- taminant reduction

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