Analysis of pulsatile flow in arteriovenous fistula through numerical simulation

This work aim to analyze the hemodynamic factors in the flow within an Arteriovenous Fistula (AVF) using a flow field calculated by numerical simulation as a visualization technique. The geometrical model is virtually reconstructed from a computed tomography scan. The considerations made are of Newt...

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Principais autores: Santos, Willyam Brito de Almeida, Rangel, Jonhattan Ferreira, Fernandes, Valquíria Bomfim, Lima, Luiz Henrique Pinheiro, Costa, Thércio Henrique de Carvalho, Bessa, Kleiber Lima de
Formato: bachelorThesis
Idioma:en_US
Publicado em: Universidade Federal do Rio Grande do Norte
Assuntos:
Arteriovenous fistula
Shear stress
Numerical simulation
Intimal hyperplasia
Endereço do item:https://repositorio.ufrn.br/handle/123456789/43066
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id ri-123456789-43066
record_format dspace
institution Repositório Institucional
collection RI - UFRN
language en_US
topic Arteriovenous fistula
Shear stress
Numerical simulation
Intimal hyperplasia
spellingShingle Arteriovenous fistula
Shear stress
Numerical simulation
Intimal hyperplasia
Santos, Willyam Brito de Almeida
Rangel, Jonhattan Ferreira
Fernandes, Valquíria Bomfim
Lima, Luiz Henrique Pinheiro
Costa, Thércio Henrique de Carvalho
Bessa, Kleiber Lima de
Analysis of pulsatile flow in arteriovenous fistula through numerical simulation
description This work aim to analyze the hemodynamic factors in the flow within an Arteriovenous Fistula (AVF) using a flow field calculated by numerical simulation as a visualization technique. The geometrical model is virtually reconstructed from a computed tomography scan. The considerations made are of Newtonian fluid, laminar and incompressible flow and pulsatile flow. Primary and secondary flows are observed in the velocity field along the AVF. In the artery, the velocity profile is typical of a laminar flow. In the anastomosis and distal regions, axial and radial recirculations are observed. The maximum velocity calculated along the AVF is 1.38 m/s. The maximum wall shear stress is of 49 Pa and shows no uniformity, varying according to velocity. The presence of recirculations allows blood formed elements to collide excessively against the endothelial wall. At regions with wall shear stress above 35 Pa, the endothelial cells can suffer damage and myointimal hyperplasia may form.
author2 Bessa, Kleiber Lima de
author_facet Bessa, Kleiber Lima de
Santos, Willyam Brito de Almeida
Rangel, Jonhattan Ferreira
Fernandes, Valquíria Bomfim
Lima, Luiz Henrique Pinheiro
Costa, Thércio Henrique de Carvalho
Bessa, Kleiber Lima de
format bachelorThesis
author Santos, Willyam Brito de Almeida
Rangel, Jonhattan Ferreira
Fernandes, Valquíria Bomfim
Lima, Luiz Henrique Pinheiro
Costa, Thércio Henrique de Carvalho
Bessa, Kleiber Lima de
author_sort Santos, Willyam Brito de Almeida
title Analysis of pulsatile flow in arteriovenous fistula through numerical simulation
title_short Analysis of pulsatile flow in arteriovenous fistula through numerical simulation
title_full Analysis of pulsatile flow in arteriovenous fistula through numerical simulation
title_fullStr Analysis of pulsatile flow in arteriovenous fistula through numerical simulation
title_full_unstemmed Analysis of pulsatile flow in arteriovenous fistula through numerical simulation
title_sort analysis of pulsatile flow in arteriovenous fistula through numerical simulation
publisher Universidade Federal do Rio Grande do Norte
publishDate 2018
url https://repositorio.ufrn.br/handle/123456789/43066
work_keys_str_mv AT santoswillyambritodealmeida analysisofpulsatileflowinarteriovenousfistulathroughnumericalsimulation
AT rangeljonhattanferreira analysisofpulsatileflowinarteriovenousfistulathroughnumericalsimulation
AT fernandesvalquiriabomfim analysisofpulsatileflowinarteriovenousfistulathroughnumericalsimulation
AT limaluizhenriquepinheiro analysisofpulsatileflowinarteriovenousfistulathroughnumericalsimulation
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spelling ri-123456789-430662021-10-05T16:02:25Z Analysis of pulsatile flow in arteriovenous fistula through numerical simulation Santos, Willyam Brito de Almeida Rangel, Jonhattan Ferreira Fernandes, Valquíria Bomfim Lima, Luiz Henrique Pinheiro Costa, Thércio Henrique de Carvalho Bessa, Kleiber Lima de Bessa, Kleiber Lima de Bessa, Kleiber Lima de Tapia, Gabriel Ivan Medina Costa, Thercio Henrique de Carvalho Arteriovenous fistula Shear stress Numerical simulation Intimal hyperplasia This work aim to analyze the hemodynamic factors in the flow within an Arteriovenous Fistula (AVF) using a flow field calculated by numerical simulation as a visualization technique. The geometrical model is virtually reconstructed from a computed tomography scan. The considerations made are of Newtonian fluid, laminar and incompressible flow and pulsatile flow. Primary and secondary flows are observed in the velocity field along the AVF. In the artery, the velocity profile is typical of a laminar flow. In the anastomosis and distal regions, axial and radial recirculations are observed. The maximum velocity calculated along the AVF is 1.38 m/s. The maximum wall shear stress is of 49 Pa and shows no uniformity, varying according to velocity. The presence of recirculations allows blood formed elements to collide excessively against the endothelial wall. At regions with wall shear stress above 35 Pa, the endothelial cells can suffer damage and myointimal hyperplasia may form. This work aim to analyze the hemodynamic factors in the flow within an Arteriovenous Fistula (AVF) using a flow field calculated by numerical simulation as a visualization technique. The geometrical model is virtually reconstructed from a computed tomography scan. The considerations made are of Newtonian fluid, laminar and incompressible flow and pulsatile flow. Primary and secondary flows are observed in the velocity field along the AVF. In the artery, the velocity profile is typical of a laminar flow. In the anastomosis and distal regions, axial and radial recirculations are observed. The maximum velocity calculated along the AVF is 1.38 m/s. The maximum wall shear stress is of 49 Pa and shows no uniformity, varying according to velocity. The presence of recirculations allows blood formed elements to collide excessively against the endothelial wall. At regions with wall shear stress above 35 Pa, the endothelial cells can suffer damage and myointimal hyperplasia may form. 2018-07-10T13:30:09Z 2021-10-05T16:02:25Z 2018-07-10T13:30:09Z 2021-10-05T16:02:25Z 2018-06-28 bachelorThesis 2016008498 BASSIOUNY, H.S. et al. Anastomotic intimal hyperplasia: mechanical injury or flow induced. Journal of Vascular Surgery, Chicago, v. 15, p. 708-716, 1992. BESSA, K.L. Análise comparativa de fluxo em fístula arteriovenosa. 2004. 169 f. Dissertação (Mestrado em Engenharia Mecânica) – Escola Politécnica da Universidade de São Paulo, São Paulo, 2004. BESSA, K.L.; ORTIZ, J.P. Flow visualization in arteriovenous fistula and aneurysm using computational fluid dynamics. Journal of Visualization, Tokyo, v. 12, p. 95-107, 2009. CARROL, G.T. et al. Realistic temporal variations of shear stress modulate MMP-2 and MCP-1 expression in arteriovenous vascular access. Cellular and Molecular Bioengineering, New York, v. 2, p. 591-605, 2011. CARROL, G.T. et al. Wall shear stresses remain elevated in mature arteriovenous fistulas: a case study. Journal of Biomechanical Engineering, New York, v. 133, 2011. FRY, D.L. Acute vascular endotelial changes associated with increased blood velocity gradientes. Circulation Research, Baltimore, v. 22, p. 165-197, 1968. GIDDENS, D. P.; ZARINS, C. K.; GLAGOV, S. The role of fluid mechanics in the localization and detection of atherosclerosis. Journal of Biomechanical Engineering, New York, v. 115, p. 588-594, 1993. GILL, S. et al. Multi-disciplinary vascular access care and access outcomes in people starting hemodialysis therapy. Clinical Journal of the American Society of Nephrology: CJASN, Washington, v. 12, p. 1-9, 2017. Acesso em: 02 out. 2017. doi: 10.2215/CJN.03430317. LINARDI, F. et al. Acesso vascular para hemodiálise: Avaliação do tipo e local anatômico em 23 unidades de diálise distribuídas em sete estados brasilieiros. Revista do Colégio Brasileiro de Cirurgiões, Rio de Janeiro, v. 30, p. 183-193, 2003. LOK, C.E. Fistula First Initiative: Advantages and Pitfalls. Clinical Journal of the American Society of Nephrology, Washington, v. xxx, p. 1043-1053, 2017. Disponível em: <cjasn.asnjournals.org/content/2/5/1043.logn>. Acesso em: 02 out. 2017. doi: 10.2215/CJN.01080307. PERRAULT, L.P. et al. Effects of the occlusion devices for minimally invasive coronary artery bypass surgery on coronary endothelial function of atherosclerosis arteries., The Heart Surgery Forum, Virginia, v. 3, p. 287-292, 2000. RUBANYI, G.M. The role of endothelium in cardiovascular homeostasis. Journal of cardiovascular pharmacology, New York, v. 22, p. S1-S14, 1993. SIGOVAN, M. et al. Vascular remodeling in autogenous arterio-venous fistulas by MRI and CFD. Annals of Biomedical Engineering, New York, v. 41, p. 657-668, 2013. SIVANESAN, S.; HOW, T.V.; BAKRAN, A. Sites of stenosis in AV fistulae for haemodialysis access. Nephrology, dialysis, transplantation: official publication of the European Dialysis and Transplant Assocciation – European Renal Association, Oxford, v. 14, p. 118-120, 1999. https://repositorio.ufrn.br/handle/123456789/43066 en_US openAccess application/pdf Universidade Federal do Rio Grande do Norte Brasil UFRN Engenharia Mecânica

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