Extrato a base de taninos da casca da Azadirachta indica A Juss. e seu potencial antioxidante e antibacteriano
The search for alternative medicines of natural origin is growing, mainly due to the inefficiency of the drugs currently used for the treatment of diseases caused by super-bacteria and/or oxidative stresses. The barks of plants, on the other hand, present themselves as a source of bioactive capable...
Na minha lista:
| Autor principal: | |
|---|---|
| Outros Autores: | |
| Formato: | bachelorThesis |
| Idioma: | pt_BR |
| Publicado em: |
Universidade Federal do Rio Grande do Norte
|
| Assuntos: | |
| Endereço do item: | https://repositorio.ufrn.br/handle/123456789/38286 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|
| Resumo: | The search for alternative medicines of natural origin is growing, mainly due to the inefficiency of the drugs currently used for the treatment of diseases caused by super-bacteria and/or oxidative stresses. The barks of plants, on the other hand, present themselves as a source of bioactive capable of treating different diseases. Among the chemical compounds of the barks with medicinal properties, tannins stand out. Thus, this work aimed to characterize and verify the antioxidant and antimicrobial potential of the tannin-based extract of the stem bark of Azadirachta indica A Juss. The bark was collected from five individuals located in the experimental plantation of the Federal University of Rio Grande do Norte, Macaíba Campus. They were dried and ground to reduce their granulometry. Then the phenolic compounds were extracted and the total solid content (TST), Stiasny index (I), condensed tannin content (CTT), non-tannin content (NTC), and tannins per ton of dry bark were determined. Antioxidant activity was determined by the DPPH method. For antimicrobial activity, the disk diffusion method was applied using gram-positive and negative bacteria. The mean value found for TST, I, TTC was 6.91, 67.4, and 6.88%, respectively. The antioxidant activity showed an IC50 value of 4.69 µg/mL-1. The most sensitive bacteria to the use of tannic extract was Staphylococcus aureus, with an average halo of inhibition of 12.4 mm. Therefore, the tannic extract of A. indica presents itself as a source of bioactive with therapeutic capacity and can serve as a basis for the development of different products in the pharmaceutical, cosmetic, and food industries. |
|---|