Análise do nível sérico de bilirrubina como indicador de risco para a deficiência auditiva retrococlear na infância
Introduction: Excess bilirubin in the blood may cause damage to the auditory system due to its neurotoxic character. Ergo, the emergence of retrocochlear alterations induced by this factor is possible, and hyperbilirubinemia is considered a risk factor for hearing loss. Objective: To analyze the ser...
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| Formato: | bachelorThesis |
| Idioma: | pt_BR |
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Universidade Federal do Rio Grande do Norte
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| Endereço do item: | https://repositorio.ufrn.br/handle/123456789/36027 |
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| Resumo: | Introduction: Excess bilirubin in the blood may cause damage to the auditory system due to its neurotoxic character. Ergo, the emergence of retrocochlear alterations induced by this factor is possible, and hyperbilirubinemia is considered a risk factor for hearing loss. Objective: To analyze the serum levels of Total Bilirubin (TB) and its influence on hearing loss, as well as to verify if there is interference of TB level on the medial olivocochlear efferent system. Method: This is a descriptive study, structured in two steps: (1) analysis of serum bilirubin level as risk factor in audiological monitoring and (2) suppression effect of otoacoustic emissions in infants and children with a history of neonatal icterus/ hyperbilirubinemia. Stage 1 had 27 children, aged between four and 38 months, referred for monitoring and in stage 2, 12 individuals participated, aged between one and 35 months, referred for neonatal hearing screening or audiological monitoring and who underwent the Transient Evoked Otoacoustic Emissions test with suppression. Data were submitted to descriptive and inferential statistical analysis, adopting a significance level of 5%. Results: We show that 76.9% of referrals were due to neonatal icterus with phototherapy, no child presented disabling hearing loss, however 30% of the individuals presented reversible changes. All children had the suppression effect. Conclusion: There was no disabling hearing loss associated with the studied TB levels. Suppression occurred regardless of TB level and gestational age. |
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