Suplementação de vitamina C e D e a gravidade de COVID-19
Context: The Covid-19 pandemic quickly spread to other countries, causing numerous deaths. Diet and nutrition invariably influence the competence of the immune system and determine the risk and severity of infections. Methods: In this context, this protocol describes a systematic review aiming to an...
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| Formato: | Dissertação |
| Idioma: | pt_BR |
| Publicado em: |
Universidade Federal do Rio Grande do Norte
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| Endereço do item: | https://repositorio.ufrn.br/handle/123456789/33297 |
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| Resumo: | Context: The Covid-19 pandemic quickly spread to other countries, causing numerous
deaths. Diet and nutrition invariably influence the competence of the immune system
and determine the risk and severity of infections. Methods: In this context, this protocol
describes a systematic review aiming to analyze whether vitamin C and D
supplementation can reduce the severity of Covid-19. This protocol was developed
based on the PRISMA-P recommendations. To carry out the systematic review, we will
perform searches in the PubMed, Web of Science, Scopus, Cochrane and
ScienceDirect databases in search of case-control studies that analyze the
supplementation and evolution of patients with COVID-19. There will be no limitations
related to language or time of publication. Searches will be performed by two
independent researchers who will select articles and then duplicate studies will be
removed, while suitable ones will be selected using the Rayyan QCRI application. To
assess the risk of bias, we will use the instrument proposed by the National Heart,
Lung and Blood Institute. In addition, we will perform meta-analyses and subgroup
analyzes according to the conditions of the included data. Results: This review will
assess the association between vitamin C and D supplementation and reduced
severity of COVID-19. Conclusion: The results of this systematic review will summarize
the latest evidence for the association between vitamin C and D supplementation and
COVID-19 through a systematic review and meta-analysis. |
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