Divergent low-density lipoprotein receptor (LDLR) linked to low VSV G-dependent viral infectivity and unique serum lipid profile in zebra finches

The low-density lipoprotein receptor (LDLR) is key to cellular cholesterol uptake and is also the main receptor for the vesicular stomatitis virus glycoprotein (VSV G). Here we show that in songbirds LDLR is highly divergent and lacks domains critical for ligand binding and cellular trafficking, inc...

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Detalhes bibliográficos
Principais autores:	Velho, Tarciso André Ferreira, Lovell, Peter V, Friedrich, Samantha R, Olson, Christopher R, Miles, Joshua, Mueller, Paul A, Tavori, Hagai, Fazio, Sergio, Lois, Carlos, Mello, Claudio V
Formato:	article
Idioma:	English
Publicado em:
Assuntos:	Cholesterol LDLR VSG G Lentivirus Viral transduction
Endereço do item:	https://repositorio.ufrn.br/handle/123456789/32808 https://doi.org/10.1073/pnas.2025167118
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