Psychotropics in different causes of itch: systematic review with controlled studies

Among the wide range of symptoms neglected or resistant to conventional treatments in clinical practice, itch is emerging gradually as a theme to be studied. Itch complaints and the negative effects in the quality of life are observed in several medical fields. Although the partially obscure pathoph...

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Principais autores:	Brasileiro, Lízie Emanuelle Eulalio, Barreto, Dayanna Patrícia de Carvalho, Nunes, Emerson Arcoverde
Formato:	article
Idioma:	English
Publicado em:	Sociedade Brasileira de Dermatologia
Assuntos:	Pruritus Psychotropic drugs Controlled clinical trial
Endereço do item:	https://repositorio.ufrn.br/handle/123456789/31031
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spelling	ri-123456789-310312020-12-20T07:59:13Z Psychotropics in different causes of itch: systematic review with controlled studies Brasileiro, Lízie Emanuelle Eulalio Barreto, Dayanna Patrícia de Carvalho Nunes, Emerson Arcoverde Pruritus Psychotropic drugs Controlled clinical trial Among the wide range of symptoms neglected or resistant to conventional treatments in clinical practice, itch is emerging gradually as a theme to be studied. Itch complaints and the negative effects in the quality of life are observed in several medical fields. Although the partially obscure pathophysiology, some researchers decided to check and test the use of psychotropic drugs in resistant itch to conventional topical treatments and antihistamines. The objective of this study was to evaluate scientific evidence in psychotropic use in the treatment of itch of various causes. This is a systematic review of scientific literature. The following databases were used: PubMed, Web of Science, Scopus and Scielo. Randomized controlled trials that should focus on treatment with psychotropic drugs of pruritus of various causes were the inclusion criteria. All articles were analyzed by the authors, and the consensus was reached in cases of disagreement. Fifteen articles were included after analysis and selection in databases, with the majority of clinical trials focusing on psychopharmacological treatment of itch on account of chronic kidney disease. Clinical trials with psychotropic drugs mostly indicated significant improvement in the itching. In most trials of chronic kidney disease as basal disease for itch, greater effectiveness was observed with the use of psychotropic drugs compared with placebo or other antipruritic. However, the small amount of controlled trials conducted precludes the generalization that psychiatric drugs are effective for itch of various causes 2020-12-17T12:08:15Z 2020-12-17T12:08:15Z 2016-12 article BRASILEIRO, Lízie Emanuelle Eulalio; BARRETO, Dayanna Patrícia de Carvalho; NUNES, Emerson Arcoverde. Psychotropics in different causes of itch: systematic review with controlled studies. Anais Brasileiros de Dermatologia, [s. l.], v. 91, n. 6, p. 791-798, dez. 2016. Disponível em: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000600791&lng=en&tlng=en. Acesso em: 16 out. 2020. http://dx.doi.org/10.1590/abd1806-4841.20164878 0365-0596 1806-4841 https://repositorio.ufrn.br/handle/123456789/31031 10.1590/abd1806-4841.20164878 en Attribution-NonCommercial 3.0 Brazil http://creativecommons.org/licenses/by-nc/3.0/br/ application/pdf Sociedade Brasileira de Dermatologia
institution	Repositório Institucional
collection	RI - UFRN
language	English
topic	Pruritus Psychotropic drugs Controlled clinical trial
spellingShingle	Pruritus Psychotropic drugs Controlled clinical trial Brasileiro, Lízie Emanuelle Eulalio Barreto, Dayanna Patrícia de Carvalho Nunes, Emerson Arcoverde Psychotropics in different causes of itch: systematic review with controlled studies
description	Among the wide range of symptoms neglected or resistant to conventional treatments in clinical practice, itch is emerging gradually as a theme to be studied. Itch complaints and the negative effects in the quality of life are observed in several medical fields. Although the partially obscure pathophysiology, some researchers decided to check and test the use of psychotropic drugs in resistant itch to conventional topical treatments and antihistamines. The objective of this study was to evaluate scientific evidence in psychotropic use in the treatment of itch of various causes. This is a systematic review of scientific literature. The following databases were used: PubMed, Web of Science, Scopus and Scielo. Randomized controlled trials that should focus on treatment with psychotropic drugs of pruritus of various causes were the inclusion criteria. All articles were analyzed by the authors, and the consensus was reached in cases of disagreement. Fifteen articles were included after analysis and selection in databases, with the majority of clinical trials focusing on psychopharmacological treatment of itch on account of chronic kidney disease. Clinical trials with psychotropic drugs mostly indicated significant improvement in the itching. In most trials of chronic kidney disease as basal disease for itch, greater effectiveness was observed with the use of psychotropic drugs compared with placebo or other antipruritic. However, the small amount of controlled trials conducted precludes the generalization that psychiatric drugs are effective for itch of various causes
format	article
author	Brasileiro, Lízie Emanuelle Eulalio Barreto, Dayanna Patrícia de Carvalho Nunes, Emerson Arcoverde
author_facet	Brasileiro, Lízie Emanuelle Eulalio Barreto, Dayanna Patrícia de Carvalho Nunes, Emerson Arcoverde
author_sort	Brasileiro, Lízie Emanuelle Eulalio
title	Psychotropics in different causes of itch: systematic review with controlled studies
title_short	Psychotropics in different causes of itch: systematic review with controlled studies
title_full	Psychotropics in different causes of itch: systematic review with controlled studies
title_fullStr	Psychotropics in different causes of itch: systematic review with controlled studies
title_full_unstemmed	Psychotropics in different causes of itch: systematic review with controlled studies
title_sort	psychotropics in different causes of itch: systematic review with controlled studies
publisher	Sociedade Brasileira de Dermatologia
publishDate	2020
url	https://repositorio.ufrn.br/handle/123456789/31031
work_keys_str_mv	AT brasileirolizieemanuelleeulalio psychotropicsindifferentcausesofitchsystematicreviewwithcontrolledstudies AT barretodayannapatriciadecarvalho psychotropicsindifferentcausesofitchsystematicreviewwithcontrolledstudies AT nunesemersonarcoverde psychotropicsindifferentcausesofitchsystematicreviewwithcontrolledstudies
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Psychotropics in different causes of itch: systematic review with controlled studies

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