Exome sequencing of native populations from the Amazon reveals patterns on the peopling of South America

Studies on the peopling of South America have been limited by the paucity of sequence data from Native Americans, especially from the east part of the Amazon region. Here, we investigate the whole exome variation from 58 Native American individuals (eight different populations) from the Amazon regio...

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Principais autores:	Ribeiro-dos-Santos, André M., Vidal, Amanda Ferreira, Vinasco-Sandoval, Tatiana, Guerreiro, João, Santos, Sidney, Ribeiro-dos-Santos, Ândrea, Souza, Sandro José de
Formato:	article
Idioma:	English
Publicado em:	Frontiers Media SA
Assuntos:	Amazon Native populations Exome Genomics SNP (Single Nucleotide Polymorphism)
Endereço do item:	https://repositorio.ufrn.br/handle/123456789/30514 https://doi.org/10.3389/fgene.2020.548507
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id	ri-123456789-30514
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spelling	ri-123456789-305142020-11-01T08:19:44Z Exome sequencing of native populations from the Amazon reveals patterns on the peopling of South America Ribeiro-dos-Santos, André M. Vidal, Amanda Ferreira Vinasco-Sandoval, Tatiana Guerreiro, João Santos, Sidney Ribeiro-dos-Santos, Ândrea Souza, Sandro José de Amazon Native populations Exome Genomics SNP (Single Nucleotide Polymorphism) Studies on the peopling of South America have been limited by the paucity of sequence data from Native Americans, especially from the east part of the Amazon region. Here, we investigate the whole exome variation from 58 Native American individuals (eight different populations) from the Amazon region and draw insights into the peopling of South America. By using the sequence data generated here together with data from the public domain, we confirmed a strong genetic distinction between Andean and Amazonian populations. By testing distinct demographic models, our analysis supports a scenario of South America occupation that involves migrations along the Pacific and Atlantic coasts. Occupation of the southeast part of South America would involve migrations from the north, rather than from the west of the continent 2020-10-29T18:26:58Z 2020-10-29T18:26:58Z 2020-10-29 article RIBEIRO-DOS-SANTOS, André M.; VIDAL, Amanda Ferreira; VINASCO-SANDOVAL, Tatiana; GUERREIRO, João; SANTOS, Sidney; RIBEIRO-DOS-SANTOS, Ândrea; SOUZA, Sandro José de. Exome sequencing of native populations from the Amazon reveals patterns on the peopling of South America. Frontiers In Genetics, [S. l.], v. 11, p. 548505, out. 2020. http://dx.doi.org/10.3389/fgene.2020.548507. Disponível em: https://www.frontiersin.org/articles/10.3389/fgene.2020.548507/full?utm_source=F-NTF&utm_medium=EMLX&utm_campaign=PRD_FEOPS_20170000_ARTICLE. Acesso em: 29 out. 2020. https://repositorio.ufrn.br/handle/123456789/30514 https://doi.org/10.3389/fgene.2020.548507 en Attribution 3.0 Brazil http://creativecommons.org/licenses/by/3.0/br/ application/pdf Frontiers Media SA
institution	Repositório Institucional
collection	RI - UFRN
language	English
topic	Amazon Native populations Exome Genomics SNP (Single Nucleotide Polymorphism)
spellingShingle	Amazon Native populations Exome Genomics SNP (Single Nucleotide Polymorphism) Ribeiro-dos-Santos, André M. Vidal, Amanda Ferreira Vinasco-Sandoval, Tatiana Guerreiro, João Santos, Sidney Ribeiro-dos-Santos, Ândrea Souza, Sandro José de Exome sequencing of native populations from the Amazon reveals patterns on the peopling of South America
description	Studies on the peopling of South America have been limited by the paucity of sequence data from Native Americans, especially from the east part of the Amazon region. Here, we investigate the whole exome variation from 58 Native American individuals (eight different populations) from the Amazon region and draw insights into the peopling of South America. By using the sequence data generated here together with data from the public domain, we confirmed a strong genetic distinction between Andean and Amazonian populations. By testing distinct demographic models, our analysis supports a scenario of South America occupation that involves migrations along the Pacific and Atlantic coasts. Occupation of the southeast part of South America would involve migrations from the north, rather than from the west of the continent
format	article
author	Ribeiro-dos-Santos, André M. Vidal, Amanda Ferreira Vinasco-Sandoval, Tatiana Guerreiro, João Santos, Sidney Ribeiro-dos-Santos, Ândrea Souza, Sandro José de
author_facet	Ribeiro-dos-Santos, André M. Vidal, Amanda Ferreira Vinasco-Sandoval, Tatiana Guerreiro, João Santos, Sidney Ribeiro-dos-Santos, Ândrea Souza, Sandro José de
author_sort	Ribeiro-dos-Santos, André M.
title	Exome sequencing of native populations from the Amazon reveals patterns on the peopling of South America
title_short	Exome sequencing of native populations from the Amazon reveals patterns on the peopling of South America
title_full	Exome sequencing of native populations from the Amazon reveals patterns on the peopling of South America
title_fullStr	Exome sequencing of native populations from the Amazon reveals patterns on the peopling of South America
title_full_unstemmed	Exome sequencing of native populations from the Amazon reveals patterns on the peopling of South America
title_sort	exome sequencing of native populations from the amazon reveals patterns on the peopling of south america
publisher	Frontiers Media SA
publishDate	2020
url	https://repositorio.ufrn.br/handle/123456789/30514 https://doi.org/10.3389/fgene.2020.548507
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Exome sequencing of native populations from the Amazon reveals patterns on the peopling of South America

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