Activity Cliff como ferramenta na análise da relação estrutura atividade em uma série de inibidores da enzima FabH bacteriana
The synthesis of fatty acids, mainly by the enzyme β-ketoacyl-ACP synthase III (FabH), has been emerging as an excellent target for new molecules with antimicrobial action. Despite the urgency generated by increasing bacterial resistance, the synthesis of new molecules is a very expensive task in...
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| Materialtyp: | Dissertação |
| Språk: | pt_BR |
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| Länkar: | https://repositorio.ufrn.br/jspui/handle/123456789/26845 |
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