Melhoria da qualidade do processo de dispensação ambulatorial de medicamentos antineoplásicos orais
Introduction: In Brazil, since the second half of the 20th century, because of the changes in the demographic profile and in population’s morbidity and mortality, an increase has been observed in chronic degenerative diseases, what includes cancer. In its treatment, the use of orally administered...
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| Formato: | Dissertação |
| Idioma: | por |
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| Endereço do item: | https://repositorio.ufrn.br/jspui/handle/123456789/26470 |
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| Resumo: | Introduction: In Brazil, since the second half of the 20th century, because of the
changes in the demographic profile and in population’s morbidity and mortality, an
increase has been observed in chronic degenerative diseases, what includes cancer.
In its treatment, the use of orally administered medications is increasing, they tend to
be more convenient, but also increase the risk of adverse events. This fact reinforces
the importance of consolidating its qualified and safe use, specifically at the
dispensation stage, which should have a preventive and corrective nature in this
process. Purpose: To evaluate and promote the process suitability of outpatient
dispensing, administered with oral antineoplastic medications, through an
improvement cycle. Methodology: This is a quantitative, near-experimental design,
before-after and without control group study, carried out at a referral hospital in the
treatment of cancer, located in the north of Minas Gerais. In which, from seven,
previously defined and validated quality criteria, the quality level of the outpatient
dispensing process of oral antineoplastics was evaluated, and based on the most
problematic criteria, improvement interventions were implemented followed by a
quality reassessment. The quality compliance of randomly selected samples (n=60)
was estimated in a timely manner and in a 95% confidence interval, as well as the
statistical significance of the achieved improvement was treated with Z test.
Outcomes: It was noticed that all seven quality criteria evaluated, showed acrossevaluation improvements. Most of them (four out of seven) had a statistically significant
increase in quality levels (p<0.05), with a relative improvement of at least 75%. In
absolute data, it was noticed that the non-compliance decreased from 148 in the first
evaluation to 67 in the re-evaluation, what represents a 54.7% improvement.
Conclusion: The study provided an evaluation of the process of outpatient dispensing,
administered with oral antineoplastics in the institution, identifying the quality criteria,
what favored the prioritization and effectiveness of the interventions. The improvement
cycle contributed to the inclusion of good dispensing practices and to a better
involvement of the staff with regards to quality requirements. |
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