Azilsartan Increases Levels of IL-10, Down-Regulates MMP-2, MMP-9, RANKL/RANK, Cathepsin K and Up- Regulates OPG in an Experimental Periodontitis Model
Aims The aim of this study was to evaluate the effects of azilsartan (AZT) on bone loss, inflammation, and the expression of matrix metallo proteinases (MMPs), receptor activator of nuclear factor κB ligand (RANKL), receptor activator of nuclear factor κB (RANK), osteoprotegerin (OPG), cyclooxygena...
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Principais autores: | Araújo, Aurigena Antunes de, Varela, Hugo, Brito, Gerly Anne de Castro, Medeiros, Caroline Addison Carvalho Xavier de, Araújo, Lorena de Souza, Nascimento, José Heriberto Oliveira do, Araújo Júnior, Raimundo Fernandes de |
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Formato: | article |
Idioma: | eng |
Publicado em: |
Faculté de Médecine de Nantes, France
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Endereço do item: | https://repositorio.ufrn.br/jspui/handle/123456789/25421 https://doi.org/10.1371/journal.pone.0096750 |
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