Tuberculose associada à AIDS: análise espacial e temporal dos coinfectados, no Estado do Rio Grande do Norte, Brasil (2001-2011)

The synergy between tuberculosis and human immunodeficiency virus (HIV) has been causing great impact on the epidemiology of tuberculosis in the Americas, whether in developed countries or those in development, setting up an emerging problem across the continent. The co-infection by the Micobacteriu...

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Autor principal: Fernandes, Maria José de Britto Costa
Outros Autores: Costa, Iris do Céu Clara
Formato: doctoralThesis
Idioma:por
Publicado em: Brasil
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Endereço do item:https://repositorio.ufrn.br/jspui/handle/123456789/24928
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Resumo:The synergy between tuberculosis and human immunodeficiency virus (HIV) has been causing great impact on the epidemiology of tuberculosis in the Americas, whether in developed countries or those in development, setting up an emerging problem across the continent. The co-infection by the Micobacterium tuberculosis and HIV has been studied in several countries, where the two infections represent important problem of public health. HIV infection can be considered one of the main risk factors that makes a person with latent tuberculosis (TBL) develop active tuberculosis. This work had as objective analyze the pattern of spatial variation in the incidence of tuberculosis (TB) and HIV co-infection your in the State of Rio Grande do Norte (RN), from January 2001 to December 2011. The study population consists of all cases of TB and TB/HIV co-infection occurred in the State of Rio Grande do Norte, reported in the database of the information system of reportable diseases (SINAN-MS) in the period analyzed. For a more consistent temporal analysis, maps were constructed considering the triennium 2001-2003 and 2004-2007 quadrennium and 2008-2011. Social and demographic information were obtained based on the 2010 census – IBGE municipality level. With respect to statistical analysis, we used GIS tools using QGIS version 2.0.1 software Dufour (www.qgis.org), spatial statistical analysis techniques to data of areas using the R-System software, version 2.15.0 (www.r-project.gov ), in addition to the SPSS, version 18. The standard way of presenting data from the area was made by using thematic maps concerning the incidence rate (TI), allowing you to see the pattern of spatial variation. It has a temporal variation with upward trend of co-infection TB/HIV, with a higher incidence in the age group of 20 to 49 years, followed by the age group 50 years ≥, the most frequent pulmonary, with predominance in males. It is expected, that this study can contribute to indicators, which help improve the targeting of resources in the routine treatment of Coinfected in the State of Rio Grande do Norte, Brazil.