Large solitary fibrous tumor of the oral cavity - Report of a case
The solitary fibrous tumor (SFT) is a rare soft tissue tumor with a substantially benign clinical behavior. The SFT of the oral cavity is a very uncommon entity. It is also of complicated diagnosis because of its extensive morphologic diversity and because of its similarity to many mesenchymal tumor...
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ri-123456789-239062021-12-07T15:20:28Z Large solitary fibrous tumor of the oral cavity - Report of a case Oliveira, Denise Hélen Imaculada Pereira de Albuquerque, Assis Filipe Medeiros Barreto, Matheus Dantas de Araújo Nonaka, Cassiano Francisco Weege Silva, José Sandro Pereira da Germano, Adriano Rocha Queiroz, Lélia Maria Guedes Solitary fibrous tumor Oral cavity Differential diagnosis Immunohistochemistry CD34 The solitary fibrous tumor (SFT) is a rare soft tissue tumor with a substantially benign clinical behavior. The SFT of the oral cavity is a very uncommon entity. It is also of complicated diagnosis because of its extensive morphologic diversity and because of its similarity to many mesenchymal tumors. A 44-year-old man was referred for management of an asymptomatic lesion in the left buccal mucosa, which had been identified 10 years earlier. Intra-oral examination revealed a well-demarcated, fibroelastic, rounded exophytic mass located in the left buccal mucosa. The mass was covered with a non-ulcerated mucosa of normal color and measured approximately 4.0 cm in diameter. Histopathological examination showed proliferation of spindle-shaped cells arranged in fascicles and in a patternless pattern, highly vascularized, with focal staghorn vessels. Immunohistochemical analysis revealed diffuse positivity for CD34 and focal positivity for Bcl-2. Awareness of the morphological diversity of SFT coupled to a judicious use of appropriate immunohistochemical probes should prove valuable to accurately segregate SFT from other spindle cell neoplasms. 2017-09-15T14:06:37Z 2017-09-15T14:06:37Z 2014 article OLIVEIRA, Denise Hélen Imaculada Pereira de et al. Large solitary fibrous tumor of the oral cavity - Report of a case. Pathology, Research and Practice, v. 210, n. 12, p. 1064-1067, 2014. https://repositorio.ufrn.br/jspui/handle/123456789/23906 https://doi.org/10.1016/j.prp.2014.09.018 eng Acesso Aberto application/pdf |
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Solitary fibrous tumor Oral cavity Differential diagnosis Immunohistochemistry CD34 |
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Solitary fibrous tumor Oral cavity Differential diagnosis Immunohistochemistry CD34 Oliveira, Denise Hélen Imaculada Pereira de Albuquerque, Assis Filipe Medeiros Barreto, Matheus Dantas de Araújo Nonaka, Cassiano Francisco Weege Silva, José Sandro Pereira da Germano, Adriano Rocha Queiroz, Lélia Maria Guedes Large solitary fibrous tumor of the oral cavity - Report of a case |
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The solitary fibrous tumor (SFT) is a rare soft tissue tumor with a substantially benign clinical behavior. The SFT of the oral cavity is a very uncommon entity. It is also of complicated diagnosis because of its extensive morphologic diversity and because of its similarity to many mesenchymal tumors. A 44-year-old man was referred for management of an asymptomatic lesion in the left buccal mucosa, which had been identified 10 years earlier. Intra-oral examination revealed a well-demarcated, fibroelastic, rounded exophytic mass located in the left buccal mucosa. The mass was covered with a non-ulcerated mucosa of normal color and measured approximately 4.0 cm in diameter. Histopathological examination showed proliferation of spindle-shaped cells arranged in fascicles and in a patternless pattern, highly vascularized, with focal staghorn vessels. Immunohistochemical analysis revealed diffuse positivity for CD34 and focal positivity for Bcl-2. Awareness of the morphological diversity of SFT coupled to a judicious use of appropriate immunohistochemical probes should prove valuable to accurately segregate SFT from other spindle cell neoplasms. |
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Oliveira, Denise Hélen Imaculada Pereira de Albuquerque, Assis Filipe Medeiros Barreto, Matheus Dantas de Araújo Nonaka, Cassiano Francisco Weege Silva, José Sandro Pereira da Germano, Adriano Rocha Queiroz, Lélia Maria Guedes |
author_facet |
Oliveira, Denise Hélen Imaculada Pereira de Albuquerque, Assis Filipe Medeiros Barreto, Matheus Dantas de Araújo Nonaka, Cassiano Francisco Weege Silva, José Sandro Pereira da Germano, Adriano Rocha Queiroz, Lélia Maria Guedes |
author_sort |
Oliveira, Denise Hélen Imaculada Pereira de |
title |
Large solitary fibrous tumor of the oral cavity - Report of a case |
title_short |
Large solitary fibrous tumor of the oral cavity - Report of a case |
title_full |
Large solitary fibrous tumor of the oral cavity - Report of a case |
title_fullStr |
Large solitary fibrous tumor of the oral cavity - Report of a case |
title_full_unstemmed |
Large solitary fibrous tumor of the oral cavity - Report of a case |
title_sort |
large solitary fibrous tumor of the oral cavity - report of a case |
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2017 |
url |
https://repositorio.ufrn.br/jspui/handle/123456789/23906 https://doi.org/10.1016/j.prp.2014.09.018 |
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