Large solitary fibrous tumor of the oral cavity - Report of a case

The solitary fibrous tumor (SFT) is a rare soft tissue tumor with a substantially benign clinical behavior. The SFT of the oral cavity is a very uncommon entity. It is also of complicated diagnosis because of its extensive morphologic diversity and because of its similarity to many mesenchymal tumor...

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Principais autores: Oliveira, Denise Hélen Imaculada Pereira de, Albuquerque, Assis Filipe Medeiros, Barreto, Matheus Dantas de Araújo, Nonaka, Cassiano Francisco Weege, Silva, José Sandro Pereira da, Germano, Adriano Rocha, Queiroz, Lélia Maria Guedes
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Endereço do item:https://repositorio.ufrn.br/jspui/handle/123456789/23906
https://doi.org/10.1016/j.prp.2014.09.018
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spelling ri-123456789-239062021-12-07T15:20:28Z Large solitary fibrous tumor of the oral cavity - Report of a case Oliveira, Denise Hélen Imaculada Pereira de Albuquerque, Assis Filipe Medeiros Barreto, Matheus Dantas de Araújo Nonaka, Cassiano Francisco Weege Silva, José Sandro Pereira da Germano, Adriano Rocha Queiroz, Lélia Maria Guedes Solitary fibrous tumor Oral cavity Differential diagnosis Immunohistochemistry CD34 The solitary fibrous tumor (SFT) is a rare soft tissue tumor with a substantially benign clinical behavior. The SFT of the oral cavity is a very uncommon entity. It is also of complicated diagnosis because of its extensive morphologic diversity and because of its similarity to many mesenchymal tumors. A 44-year-old man was referred for management of an asymptomatic lesion in the left buccal mucosa, which had been identified 10 years earlier. Intra-oral examination revealed a well-demarcated, fibroelastic, rounded exophytic mass located in the left buccal mucosa. The mass was covered with a non-ulcerated mucosa of normal color and measured approximately 4.0 cm in diameter. Histopathological examination showed proliferation of spindle-shaped cells arranged in fascicles and in a patternless pattern, highly vascularized, with focal staghorn vessels. Immunohistochemical analysis revealed diffuse positivity for CD34 and focal positivity for Bcl-2. Awareness of the morphological diversity of SFT coupled to a judicious use of appropriate immunohistochemical probes should prove valuable to accurately segregate SFT from other spindle cell neoplasms. 2017-09-15T14:06:37Z 2017-09-15T14:06:37Z 2014 article OLIVEIRA, Denise Hélen Imaculada Pereira de et al. Large solitary fibrous tumor of the oral cavity - Report of a case. Pathology, Research and Practice, v. 210, n. 12, p. 1064-1067, 2014. https://repositorio.ufrn.br/jspui/handle/123456789/23906 https://doi.org/10.1016/j.prp.2014.09.018 eng Acesso Aberto application/pdf
institution Repositório Institucional
collection RI - UFRN
language eng
topic Solitary fibrous tumor
Oral cavity
Differential diagnosis
Immunohistochemistry
CD34
spellingShingle Solitary fibrous tumor
Oral cavity
Differential diagnosis
Immunohistochemistry
CD34
Oliveira, Denise Hélen Imaculada Pereira de
Albuquerque, Assis Filipe Medeiros
Barreto, Matheus Dantas de Araújo
Nonaka, Cassiano Francisco Weege
Silva, José Sandro Pereira da
Germano, Adriano Rocha
Queiroz, Lélia Maria Guedes
Large solitary fibrous tumor of the oral cavity - Report of a case
description The solitary fibrous tumor (SFT) is a rare soft tissue tumor with a substantially benign clinical behavior. The SFT of the oral cavity is a very uncommon entity. It is also of complicated diagnosis because of its extensive morphologic diversity and because of its similarity to many mesenchymal tumors. A 44-year-old man was referred for management of an asymptomatic lesion in the left buccal mucosa, which had been identified 10 years earlier. Intra-oral examination revealed a well-demarcated, fibroelastic, rounded exophytic mass located in the left buccal mucosa. The mass was covered with a non-ulcerated mucosa of normal color and measured approximately 4.0 cm in diameter. Histopathological examination showed proliferation of spindle-shaped cells arranged in fascicles and in a patternless pattern, highly vascularized, with focal staghorn vessels. Immunohistochemical analysis revealed diffuse positivity for CD34 and focal positivity for Bcl-2. Awareness of the morphological diversity of SFT coupled to a judicious use of appropriate immunohistochemical probes should prove valuable to accurately segregate SFT from other spindle cell neoplasms.
format article
author Oliveira, Denise Hélen Imaculada Pereira de
Albuquerque, Assis Filipe Medeiros
Barreto, Matheus Dantas de Araújo
Nonaka, Cassiano Francisco Weege
Silva, José Sandro Pereira da
Germano, Adriano Rocha
Queiroz, Lélia Maria Guedes
author_facet Oliveira, Denise Hélen Imaculada Pereira de
Albuquerque, Assis Filipe Medeiros
Barreto, Matheus Dantas de Araújo
Nonaka, Cassiano Francisco Weege
Silva, José Sandro Pereira da
Germano, Adriano Rocha
Queiroz, Lélia Maria Guedes
author_sort Oliveira, Denise Hélen Imaculada Pereira de
title Large solitary fibrous tumor of the oral cavity - Report of a case
title_short Large solitary fibrous tumor of the oral cavity - Report of a case
title_full Large solitary fibrous tumor of the oral cavity - Report of a case
title_fullStr Large solitary fibrous tumor of the oral cavity - Report of a case
title_full_unstemmed Large solitary fibrous tumor of the oral cavity - Report of a case
title_sort large solitary fibrous tumor of the oral cavity - report of a case
publishDate 2017
url https://repositorio.ufrn.br/jspui/handle/123456789/23906
https://doi.org/10.1016/j.prp.2014.09.018
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