Efficacy assessment of two antibiotic prophylaxis regimens in oral and maxillofacial trauma surgery: preliminary results

The study set out to evaluate the efficacy of two antibiotic prophylaxis regimens in patients with facial fractures admitted to the Oral and Maxillofacial Surgery and Traumatology services of the Onofre Lopes University Hospital attached to the Federal University of Rio Grande do Norte in the period...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Principais autores: Campos, Giordano B. P., Lucena, Eudes Euler de Souza, Silva, José Sandro Pereira da, Gomes, Petrus Pereira, Germano, Adriano Rocha
Formato: article
Idioma:eng
Publicado em:
Assuntos:
Postoperative infection
Antibiotic prophylaxis
Cefazolin
Endereço do item:https://repositorio.ufrn.br/jspui/handle/123456789/23892
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
id ri-123456789-23892
record_format dspace
spelling ri-123456789-238922021-12-09T15:21:30Z Efficacy assessment of two antibiotic prophylaxis regimens in oral and maxillofacial trauma surgery: preliminary results Campos, Giordano B. P. Lucena, Eudes Euler de Souza Silva, José Sandro Pereira da Gomes, Petrus Pereira Germano, Adriano Rocha Postoperative infection Antibiotic prophylaxis Cefazolin The study set out to evaluate the efficacy of two antibiotic prophylaxis regimens in patients with facial fractures admitted to the Oral and Maxillofacial Surgery and Traumatology services of the Onofre Lopes University Hospital attached to the Federal University of Rio Grande do Norte in the period from December 2011 to December 2012. The sample consisted of 74 patients divided into two groups, GI with forty-three patients and GII with 32. Both groups received 2 g of cefazolin, 20 minutes before surgery. The postoperative protocol for each group was randomly determined; group I (single dose) received no antibiotics after surgery but group II (24 h dosage) received 1 g of cefazolin every 6 hours for 24 hours. Postoperative infection incidence was 9.3% (seven patients), six patients in Group I and one in Group II. 85% of the infections were in mandibular fractures. Results were presented qualitatively and quantitatively and the Chi square test (taking the value for p to be < 0.05) showed no statistically significant differences in the efficacies of the two regimens in the comparisons made between the cases of fractures in the upper and middle thirds of the face with those in the lower third (mandibular fractures). Considering mandibular fractures alone, Group II proved to be more efficacious with a p value of 0.02. However, to confirm the tendency shown in the mandibular fracture treatments whereby prolonging antibiotic administration for 24 hours appeared to be beneficial, research needs to be done with much larger sample groups. 2017-09-15T13:51:49Z 2017-09-15T13:51:49Z 2015 article CAMPOS, Giordano B. P. et al. Efficacy assessment of two antibiotic prophylaxis regimens in oral and maxillofacial trauma surgery: preliminary results. International Journal of Clinical and Experimental Medicine, v. 8, n. 2, p. 2846-2852, 2015. 1940-5901 https://repositorio.ufrn.br/jspui/handle/123456789/23892 eng Acesso Aberto application/pdf
institution Repositório Institucional
collection RI - UFRN
language eng
topic Postoperative infection
Antibiotic prophylaxis
Cefazolin
spellingShingle Postoperative infection
Antibiotic prophylaxis
Cefazolin
Campos, Giordano B. P.
Lucena, Eudes Euler de Souza
Silva, José Sandro Pereira da
Gomes, Petrus Pereira
Germano, Adriano Rocha
Efficacy assessment of two antibiotic prophylaxis regimens in oral and maxillofacial trauma surgery: preliminary results
description The study set out to evaluate the efficacy of two antibiotic prophylaxis regimens in patients with facial fractures admitted to the Oral and Maxillofacial Surgery and Traumatology services of the Onofre Lopes University Hospital attached to the Federal University of Rio Grande do Norte in the period from December 2011 to December 2012. The sample consisted of 74 patients divided into two groups, GI with forty-three patients and GII with 32. Both groups received 2 g of cefazolin, 20 minutes before surgery. The postoperative protocol for each group was randomly determined; group I (single dose) received no antibiotics after surgery but group II (24 h dosage) received 1 g of cefazolin every 6 hours for 24 hours. Postoperative infection incidence was 9.3% (seven patients), six patients in Group I and one in Group II. 85% of the infections were in mandibular fractures. Results were presented qualitatively and quantitatively and the Chi square test (taking the value for p to be < 0.05) showed no statistically significant differences in the efficacies of the two regimens in the comparisons made between the cases of fractures in the upper and middle thirds of the face with those in the lower third (mandibular fractures). Considering mandibular fractures alone, Group II proved to be more efficacious with a p value of 0.02. However, to confirm the tendency shown in the mandibular fracture treatments whereby prolonging antibiotic administration for 24 hours appeared to be beneficial, research needs to be done with much larger sample groups.
format article
author Campos, Giordano B. P.
Lucena, Eudes Euler de Souza
Silva, José Sandro Pereira da
Gomes, Petrus Pereira
Germano, Adriano Rocha
author_facet Campos, Giordano B. P.
Lucena, Eudes Euler de Souza
Silva, José Sandro Pereira da
Gomes, Petrus Pereira
Germano, Adriano Rocha
author_sort Campos, Giordano B. P.
title Efficacy assessment of two antibiotic prophylaxis regimens in oral and maxillofacial trauma surgery: preliminary results
title_short Efficacy assessment of two antibiotic prophylaxis regimens in oral and maxillofacial trauma surgery: preliminary results
title_full Efficacy assessment of two antibiotic prophylaxis regimens in oral and maxillofacial trauma surgery: preliminary results
title_fullStr Efficacy assessment of two antibiotic prophylaxis regimens in oral and maxillofacial trauma surgery: preliminary results
title_full_unstemmed Efficacy assessment of two antibiotic prophylaxis regimens in oral and maxillofacial trauma surgery: preliminary results
title_sort efficacy assessment of two antibiotic prophylaxis regimens in oral and maxillofacial trauma surgery: preliminary results
publishDate 2017
url https://repositorio.ufrn.br/jspui/handle/123456789/23892
work_keys_str_mv AT camposgiordanobp efficacyassessmentoftwoantibioticprophylaxisregimensinoralandmaxillofacialtraumasurgerypreliminaryresults
AT lucenaeudeseulerdesouza efficacyassessmentoftwoantibioticprophylaxisregimensinoralandmaxillofacialtraumasurgerypreliminaryresults
AT silvajosesandropereirada efficacyassessmentoftwoantibioticprophylaxisregimensinoralandmaxillofacialtraumasurgerypreliminaryresults
AT gomespetruspereira efficacyassessmentoftwoantibioticprophylaxisregimensinoralandmaxillofacialtraumasurgerypreliminaryresults
AT germanoadrianorocha efficacyassessmentoftwoantibioticprophylaxisregimensinoralandmaxillofacialtraumasurgerypreliminaryresults
_version_ 1773962594404532224

Registros relacionados