Dendritic structure varies as a function of eccentricity in V1: a quantitative study of Nadph Diaphorase neurons in the diurnal south american rodent agouti, Dasyprocta Prymnolopha
The cerebral cortex is often described as a composite of repeated units or columns, integrating the same basic circuit. The ‘ice-cube’ model of cortical organization, and ‘canonical’ circuit, born from insights into functional architecture, still require systematic comparative data. Here we pro...
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ri-123456789-231792017-11-04T22:53:19Z Dendritic structure varies as a function of eccentricity in V1: a quantitative study of Nadph Diaphorase neurons in the diurnal south american rodent agouti, Dasyprocta Prymnolopha ROCHA, E. G. DA FREIRE, M. A. M. BAHIA, C. P. PEREIRA, A. SOSTHENES, M. C. K. SILVEIRA, L. C. L. ELSTON, G. N. PICANC¸ O-DINIZ, C. W. Agouti Area 17 Striate cortex Visual streak The cerebral cortex is often described as a composite of repeated units or columns, integrating the same basic circuit. The ‘ice-cube’ model of cortical organization, and ‘canonical’ circuit, born from insights into functional architecture, still require systematic comparative data. Here we probed the anatomy of an individual neuronal type within V1 to determine whether or not its dendritic trees are consistent with the ‘ice-cube’ model and theories of canonical circuits. In a previous report we studied the morphometric variability of NADPH-diaphorase (NADPH-d) neurons in the rat auditory, visual and somatosensory primary cortical areas. Our results suggested that the nitrergic cortical circuitry of primary sensory areas are differentially specialized, probably reflecting peculiarities of both habit and behavior of the species. In the present report we specifically quantified the dendritic trees of NADPH-d type I neurons as a function of eccentricity within V1. Individual neurons were reconstructed in 3D, and the size, branching and spacefilling of their dendritic trees were correlated with their location within the visuotopic map. We found that NADPH-d neurons became progressively smaller and less branched with progression from the central visual representation to the intermediate and peripheral visual representation. This finding suggests that aspects of cortical circuitry may vary across the cortical mantle to a greater extent that envisaged as natural variation among columns in the ‘ice-cube’ model. The systematic variation in neuronal structure as a function of eccentricity warrants further investigation to probe the general applicability of columnar models of cortical organization and canonical circuits. 2017-05-29T14:12:15Z 2017-05-29T14:12:15Z 2012 article 0306-4522 https://repositorio.ufrn.br/jspui/handle/123456789/23179 eng Acesso Aberto application/pdf |
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Agouti Area 17 Striate cortex Visual streak |
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Agouti Area 17 Striate cortex Visual streak ROCHA, E. G. DA FREIRE, M. A. M. BAHIA, C. P. PEREIRA, A. SOSTHENES, M. C. K. SILVEIRA, L. C. L. ELSTON, G. N. PICANC¸ O-DINIZ, C. W. Dendritic structure varies as a function of eccentricity in V1: a quantitative study of Nadph Diaphorase neurons in the diurnal south american rodent agouti, Dasyprocta Prymnolopha |
| description |
The cerebral cortex is often described as a composite
of repeated units or columns, integrating the same
basic circuit. The ‘ice-cube’ model of cortical organization,
and ‘canonical’ circuit, born from insights into functional
architecture, still require systematic comparative data. Here
we probed the anatomy of an individual neuronal type within
V1 to determine whether or not its dendritic trees are consistent
with the ‘ice-cube’ model and theories of canonical circuits.
In a previous report we studied the morphometric
variability of NADPH-diaphorase (NADPH-d) neurons in the
rat auditory, visual and somatosensory primary cortical
areas. Our results suggested that the nitrergic cortical circuitry
of primary sensory areas are differentially specialized,
probably reflecting peculiarities of both habit and behavior
of the species. In the present report we specifically quantified
the dendritic trees of NADPH-d type I neurons as a function
of eccentricity within V1. Individual neurons were
reconstructed in 3D, and the size, branching and spacefilling
of their dendritic trees were correlated with their
location within the visuotopic map. We found that NADPH-d
neurons became progressively smaller and less branched
with progression from the central visual representation to
the intermediate and peripheral visual representation. This
finding suggests that aspects of cortical circuitry may vary
across the cortical mantle to a greater extent that envisaged
as natural variation among columns in the ‘ice-cube’ model.
The systematic variation in neuronal structure as a function
of eccentricity warrants further investigation to probe the
general applicability of columnar models of cortical organization
and canonical circuits. |
| format |
article |
| author |
ROCHA, E. G. DA FREIRE, M. A. M. BAHIA, C. P. PEREIRA, A. SOSTHENES, M. C. K. SILVEIRA, L. C. L. ELSTON, G. N. PICANC¸ O-DINIZ, C. W. |
| author_facet |
ROCHA, E. G. DA FREIRE, M. A. M. BAHIA, C. P. PEREIRA, A. SOSTHENES, M. C. K. SILVEIRA, L. C. L. ELSTON, G. N. PICANC¸ O-DINIZ, C. W. |
| author_sort |
ROCHA, E. G. DA |
| title |
Dendritic structure varies as a function of eccentricity in V1: a quantitative study of Nadph Diaphorase neurons in the diurnal south american rodent agouti, Dasyprocta Prymnolopha |
| title_short |
Dendritic structure varies as a function of eccentricity in V1: a quantitative study of Nadph Diaphorase neurons in the diurnal south american rodent agouti, Dasyprocta Prymnolopha |
| title_full |
Dendritic structure varies as a function of eccentricity in V1: a quantitative study of Nadph Diaphorase neurons in the diurnal south american rodent agouti, Dasyprocta Prymnolopha |
| title_fullStr |
Dendritic structure varies as a function of eccentricity in V1: a quantitative study of Nadph Diaphorase neurons in the diurnal south american rodent agouti, Dasyprocta Prymnolopha |
| title_full_unstemmed |
Dendritic structure varies as a function of eccentricity in V1: a quantitative study of Nadph Diaphorase neurons in the diurnal south american rodent agouti, Dasyprocta Prymnolopha |
| title_sort |
dendritic structure varies as a function of eccentricity in v1: a quantitative study of nadph diaphorase neurons in the diurnal south american rodent agouti, dasyprocta prymnolopha |
| publishDate |
2017 |
| url |
https://repositorio.ufrn.br/jspui/handle/123456789/23179 |
| work_keys_str_mv |
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