Aggressive olfactory neuroblastoma invading the oral cavity: report of a rare case and review of the literature

Esthesioneuroblastoma, or olfactory neuroblastoma (ONB), is a rare malignant tumor of the olfactory neuroepithelium, which is normally confined to the superior one third of the nasal septum, cribriform plate, and superior turbinates but may extend to the base of the skull and intracranial space. ONB...

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Principais autores: Sarmento, Dmitry José de Santana, Henriques, Águida Cristina Gomes, Carvalho, Cyntia Helena Pereira de, Morais, Maria de Lourdes Silva Arruda de, Costa, Antonio de Lisboa Lopes, Silveira, Ericka Janine Dantas da
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Idioma:eng
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Endereço do item:https://repositorio.ufrn.br/jspui/handle/123456789/22996
http://doi.org/10.1016/j.joms.2011.11.020
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spelling ri-123456789-229962021-12-09T17:30:41Z Aggressive olfactory neuroblastoma invading the oral cavity: report of a rare case and review of the literature Sarmento, Dmitry José de Santana Henriques, Águida Cristina Gomes Carvalho, Cyntia Helena Pereira de Morais, Maria de Lourdes Silva Arruda de Costa, Antonio de Lisboa Lopes Silveira, Ericka Janine Dantas da Neuroblastoma Mouth Esthesioneuroblastoma, or olfactory neuroblastoma (ONB), is a rare malignant tumor of the olfactory neuroepithelium, which is normally confined to the superior one third of the nasal septum, cribriform plate, and superior turbinates but may extend to the base of the skull and intracranial space. ONB accounts for only 3% of all intranasal tumors, and its etiology remains unclear. The tumor can affect both children and adults, with a bimodal peak incidence between 11 and 20 years and between 51 and 60 years.1 Controversy exists regarding the origin, diagnosis, and management of ONB, mainly because of its rarity and the fact that most institutions treat only a small number of patients with this diagnosis.2; 3 ; 4 Many cases go unrecognized because of difficulties in the diagnosis of this tumor as a result of nonspecific initial symptoms (nasal obstruction, recurrent epistaxis). There are rare reports of ONB arising in the nasopharynx, ethmoid sinus, and maxillary sinus. We report a rare case of a very large ONB in a pediatric patient. The clinical appearance of the tumor and diagnostic procedure are discussed, and cases published in the literature are reviewed. 2017-05-16T13:31:38Z 2017-05-16T13:31:38Z 2012 article SARMENTO, D. J. S. et al. Aggressive olfactory neuroblastoma invading the oral cavity: report of a rare case and review of the literature. Journal of Maxillofacial & Oral Surgery, v. 70, n. 3, p. 525-257, 2012. https://repositorio.ufrn.br/jspui/handle/123456789/22996 http://doi.org/10.1016/j.joms.2011.11.020 eng Acesso Aberto application/pdf ELSEVIER
institution Repositório Institucional
collection RI - UFRN
language eng
topic Neuroblastoma
Mouth
spellingShingle Neuroblastoma
Mouth
Sarmento, Dmitry José de Santana
Henriques, Águida Cristina Gomes
Carvalho, Cyntia Helena Pereira de
Morais, Maria de Lourdes Silva Arruda de
Costa, Antonio de Lisboa Lopes
Silveira, Ericka Janine Dantas da
Aggressive olfactory neuroblastoma invading the oral cavity: report of a rare case and review of the literature
description Esthesioneuroblastoma, or olfactory neuroblastoma (ONB), is a rare malignant tumor of the olfactory neuroepithelium, which is normally confined to the superior one third of the nasal septum, cribriform plate, and superior turbinates but may extend to the base of the skull and intracranial space. ONB accounts for only 3% of all intranasal tumors, and its etiology remains unclear. The tumor can affect both children and adults, with a bimodal peak incidence between 11 and 20 years and between 51 and 60 years.1 Controversy exists regarding the origin, diagnosis, and management of ONB, mainly because of its rarity and the fact that most institutions treat only a small number of patients with this diagnosis.2; 3 ; 4 Many cases go unrecognized because of difficulties in the diagnosis of this tumor as a result of nonspecific initial symptoms (nasal obstruction, recurrent epistaxis). There are rare reports of ONB arising in the nasopharynx, ethmoid sinus, and maxillary sinus. We report a rare case of a very large ONB in a pediatric patient. The clinical appearance of the tumor and diagnostic procedure are discussed, and cases published in the literature are reviewed.
format article
author Sarmento, Dmitry José de Santana
Henriques, Águida Cristina Gomes
Carvalho, Cyntia Helena Pereira de
Morais, Maria de Lourdes Silva Arruda de
Costa, Antonio de Lisboa Lopes
Silveira, Ericka Janine Dantas da
author_facet Sarmento, Dmitry José de Santana
Henriques, Águida Cristina Gomes
Carvalho, Cyntia Helena Pereira de
Morais, Maria de Lourdes Silva Arruda de
Costa, Antonio de Lisboa Lopes
Silveira, Ericka Janine Dantas da
author_sort Sarmento, Dmitry José de Santana
title Aggressive olfactory neuroblastoma invading the oral cavity: report of a rare case and review of the literature
title_short Aggressive olfactory neuroblastoma invading the oral cavity: report of a rare case and review of the literature
title_full Aggressive olfactory neuroblastoma invading the oral cavity: report of a rare case and review of the literature
title_fullStr Aggressive olfactory neuroblastoma invading the oral cavity: report of a rare case and review of the literature
title_full_unstemmed Aggressive olfactory neuroblastoma invading the oral cavity: report of a rare case and review of the literature
title_sort aggressive olfactory neuroblastoma invading the oral cavity: report of a rare case and review of the literature
publisher ELSEVIER
publishDate 2017
url https://repositorio.ufrn.br/jspui/handle/123456789/22996
http://doi.org/10.1016/j.joms.2011.11.020
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