Alcoolemia em vítimas fatais de acidentes de trânsito no Rio Grande do Norte empregando cromatografia em fase gasosa - head space
Alcohol is one of the few psychotropic drugs that their consumption has admitted legally and sometimes encouraged by the society. Studies show alcohol as the highest consumption of drugs among young people and society in general, probably because of its availability and easy access. The abuse causes...
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Acidentes de trânsito Alcoolemia Cromatografia em fase gasosa Traffic accidents Blood alcohol concentration Gas chromatography CNPQ::CIENCIAS DA SAUDE::FARMACIA |
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Acidentes de trânsito Alcoolemia Cromatografia em fase gasosa Traffic accidents Blood alcohol concentration Gas chromatography CNPQ::CIENCIAS DA SAUDE::FARMACIA Santiago, Edna de Farias Alcoolemia em vítimas fatais de acidentes de trânsito no Rio Grande do Norte empregando cromatografia em fase gasosa - head space |
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Alcohol is one of the few psychotropic drugs that their consumption has admitted legally and sometimes encouraged by the society. Studies show alcohol as the highest consumption of drugs among young people and society in general, probably because of its availability and easy access. The abuse causes public health problems, which was closely related to the violence, socioeconomic problems and the high number of automobile accidents. Transit is one of the main sectors affected by the effects of alcohol, observing a high incidence in the studies. About half of automobile accidents occurs after the consumption of alcoholic beverage, and the vast majority of cases related to high concentrations of alcohol in the bloodstream. The relationship of drunk with traffic accidents is in fact evident everywhere in the world, including Brazil, where studies have shown a high relationship between alcohol consumption and traffic accidents. This study determined the alcohol in fatal victims of traffic accidents in the state of Rio Grande do Norte and established the profile of this population compared with those found in Brazil and other countries. Samples of blood of ethanol added to fulfillment of the standardization of chromatographic conditions and procedures for the analysis, being employed in the determination of alcohol in blood samples of 277 victims of traffic accidents, collected at the Institute of Scientific Technical Police of Rio Grande do North (ITEP) in the year 2007. The blood alcohol level was determined in these samples correlated with the sex, age and marital status of the victim and the location, day of week and month when the accident occurred, is doing a statistical analysis and outlining a profile of the victims of an accident at transit in the state of Rio Grande do Norte. The parameters of standardization studied ensured the quality of the analytical method and, consequently, to obtain reliable laboratory results. Being given the best temperature for injector (150 ºC), detector (250 ºC) and column (50 ºC) with a flow of gas in the column of 2mL/minutos and analysis of time of 12 minutes. The method was linear in the range of 0.01 to 3.2 g / L (r2 = 0.9989) with average recovery of 100.2% and precision with coefficient of variation less than 15%. The analysis carried out on victims of fatal road traffic accidents, ethanol detected in the blood in 66.43% of the victims and these, 96% showed concentration ≥ 0.2 g / L, 87.73% of victims were male, while 12.27% female. The younger age group (1535 years) was the most involved (52,35%) and most single (55.60%). The accidents occurred with greater prevalence in the day on Monday (27%) followed by Sunday (24,19%) and Saturday (15,52%) and it was found that the prevalence of injuries varied between the different months of the year, and in February (14.4%) and April (10.47%) the months that had a higher number of accidents, however this oscillation showed no statistically significant difference. Also no significant difference was observed between the tracks of concentration found in men and women. The standardized method showed to be efficient, given satisfactorily to the goals of this work, and the high levels of alcohol found in victims of fatal road traffic accidents are consistent with several studies of literature, and the profile of the victim also supported by presenting in its most young adults, male and single |
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http://lattes.cnpq.br/1783650979734333 |
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http://lattes.cnpq.br/1783650979734333 Santiago, Edna de Farias |
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masterThesis |
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Santiago, Edna de Farias |
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Santiago, Edna de Farias |
| title |
Alcoolemia em vítimas fatais de acidentes de trânsito no Rio Grande do Norte empregando cromatografia em fase gasosa - head space |
| title_short |
Alcoolemia em vítimas fatais de acidentes de trânsito no Rio Grande do Norte empregando cromatografia em fase gasosa - head space |
| title_full |
Alcoolemia em vítimas fatais de acidentes de trânsito no Rio Grande do Norte empregando cromatografia em fase gasosa - head space |
| title_fullStr |
Alcoolemia em vítimas fatais de acidentes de trânsito no Rio Grande do Norte empregando cromatografia em fase gasosa - head space |
| title_full_unstemmed |
Alcoolemia em vítimas fatais de acidentes de trânsito no Rio Grande do Norte empregando cromatografia em fase gasosa - head space |
| title_sort |
alcoolemia em vítimas fatais de acidentes de trânsito no rio grande do norte empregando cromatografia em fase gasosa - head space |
| publisher |
Universidade Federal do Rio Grande do Norte |
| publishDate |
2014 |
| url |
https://repositorio.ufrn.br/jspui/handle/123456789/13440 |
| work_keys_str_mv |
AT santiagoednadefarias alcoolemiaemvitimasfataisdeacidentesdetransitonoriograndedonorteempregandocromatografiaemfasegasosaheadspace |
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1773963169294712832 |
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ri-123456789-134402019-05-26T06:02:46Z Alcoolemia em vítimas fatais de acidentes de trânsito no Rio Grande do Norte empregando cromatografia em fase gasosa - head space Santiago, Edna de Farias http://lattes.cnpq.br/1783650979734333 http://lattes.cnpq.br/2959800336802498 Carvalho, José Melo de http://lattes.cnpq.br/3824079454047896 Schwarz, Aline http://lattes.cnpq.br/2401319567715548 Glória, Maria Beatriz Abreu http://lattes.cnpq.br/6895373188728113 Acidentes de trânsito Alcoolemia Cromatografia em fase gasosa Traffic accidents Blood alcohol concentration Gas chromatography CNPQ::CIENCIAS DA SAUDE::FARMACIA Alcohol is one of the few psychotropic drugs that their consumption has admitted legally and sometimes encouraged by the society. Studies show alcohol as the highest consumption of drugs among young people and society in general, probably because of its availability and easy access. The abuse causes public health problems, which was closely related to the violence, socioeconomic problems and the high number of automobile accidents. Transit is one of the main sectors affected by the effects of alcohol, observing a high incidence in the studies. About half of automobile accidents occurs after the consumption of alcoholic beverage, and the vast majority of cases related to high concentrations of alcohol in the bloodstream. The relationship of drunk with traffic accidents is in fact evident everywhere in the world, including Brazil, where studies have shown a high relationship between alcohol consumption and traffic accidents. This study determined the alcohol in fatal victims of traffic accidents in the state of Rio Grande do Norte and established the profile of this population compared with those found in Brazil and other countries. Samples of blood of ethanol added to fulfillment of the standardization of chromatographic conditions and procedures for the analysis, being employed in the determination of alcohol in blood samples of 277 victims of traffic accidents, collected at the Institute of Scientific Technical Police of Rio Grande do North (ITEP) in the year 2007. The blood alcohol level was determined in these samples correlated with the sex, age and marital status of the victim and the location, day of week and month when the accident occurred, is doing a statistical analysis and outlining a profile of the victims of an accident at transit in the state of Rio Grande do Norte. The parameters of standardization studied ensured the quality of the analytical method and, consequently, to obtain reliable laboratory results. Being given the best temperature for injector (150 ºC), detector (250 ºC) and column (50 ºC) with a flow of gas in the column of 2mL/minutos and analysis of time of 12 minutes. The method was linear in the range of 0.01 to 3.2 g / L (r2 = 0.9989) with average recovery of 100.2% and precision with coefficient of variation less than 15%. The analysis carried out on victims of fatal road traffic accidents, ethanol detected in the blood in 66.43% of the victims and these, 96% showed concentration ≥ 0.2 g / L, 87.73% of victims were male, while 12.27% female. The younger age group (1535 years) was the most involved (52,35%) and most single (55.60%). The accidents occurred with greater prevalence in the day on Monday (27%) followed by Sunday (24,19%) and Saturday (15,52%) and it was found that the prevalence of injuries varied between the different months of the year, and in February (14.4%) and April (10.47%) the months that had a higher number of accidents, however this oscillation showed no statistically significant difference. Also no significant difference was observed between the tracks of concentration found in men and women. The standardized method showed to be efficient, given satisfactorily to the goals of this work, and the high levels of alcohol found in victims of fatal road traffic accidents are consistent with several studies of literature, and the profile of the victim also supported by presenting in its most young adults, male and single O álcool é uma das poucas drogas psicotrópicas que tem seu consumo admitido legalmente e, às vezes, incentivado pela sociedade. Estudos mostram o álcool como a droga de maior consumo entre os jovens e na sociedade de forma geral, provavelmente devido à sua disponibilidade e fácil acesso. O uso abusivo provoca problemas de saúde pública, estando ele estreitamente relacionado com a violência, problemas sócioeconômicos e com o elevado número de acidentes automobilísticos. O trânsito é um dos principais setores afetados pelos efeitos do álcool, observandose alta incidência nos estudos realizados. Aproximadamente metade dos acidentes automobilísticos ocorre após o consumo de bebida alcoólica, estando a grande maioria dos casos relacionados com altas concentrações de álcool na circulação sanguínea. A relação da embriagues com os acidentes de trânsito é fato notório em toda parte do mundo, inclusive no Brasil, onde estudos demonstraram uma alta relação entre o consumo de álcool e os acidentes de trânsito. Este trabalho determinou a alcoolemia em vítimas fatais de acidente de trânsito no Estado do Rio Grande do Norte e estabeleceu o perfil desta população comparando com aqueles encontrados no Brasil e em outros países. Foram utilizadas amostras de sangue adicionadas de etanol para realização da padronização das condições cromatográficas e dos procedimentos de análise, sendo empregado na determinação da alcoolemia em amostras de sangue de 277 vítimas de acidente de trânsito, coletadas no Instituto Técnico Científico de Polícia do Rio Grande do Norte (ITEP) no ano de 2007. O nível de alcoolemia determinado nestas amostras foi correlacionado com o sexo, idade e estado civil da vítima e com a localização, dia da semana e mês em que os acidentes ocorreram, fazendose uma análise estatística e traçando um perfil das vítimas de acidente de trânsito no estado do Rio Grande do Norte. Os parâmetros de padronização estudados asseguraram a qualidade do método analítico e, conseqüentemente, a obtenção de resultados laboratoriais confiáveis. Sendo determinado as melhores temperaturas para injetor (150ºC), detector (250ºC) e coluna (50ºC), com um fluxo de gás na coluna de 2mL/minutos e tempo de análise de 12 minutos. O método foi linear no intervalo de 0,01 a 3,2 g/L (r2 = 0,9989), com recuperação média de 100,2% e precisão com coeficiente de variação menor que 15%. As análises realizadas em vítimas fatais de acidente de trânsito, detectaram etanol no sangue em 66,43% das vítimas e destas, 96% apresentaram concentração ≥ 0,2 g/L; 87,73% das vítimas eram do sexo masculino, enquanto que 12,27% do sexo feminino. A faixa etária jovem (1535 anos) foi a mais envolvida (52,35%) sendo a maioria solteira (55,60%). Os acidentes aconteceram com maior prevalência nos dias de segundafeira (27%), seguido do domingo (24,19%) e sábado (15,52%) e constatouse que a prevalência de acidentes oscilou entre os diferentes meses do ano, sendo fevereiro (14,4%) e abril (10,47%) os meses que apresentaram um maior número de acidentes, contudo esta oscilação não apresentou diferença estatisticamente significativa. Também não foi observado diferença significativa entre as faixas de concentração encontradas nos homens e nas mulheres. O método padronizado demonstrouse eficiente, atendendo satisfatoriamente aos objetivos deste trabalho; e os níveis elevados de alcoolemia encontrados nas vítimas fatais de acidente de trânsito são coincidentes com vários estudos da literatura, sendo o perfil da vítima também compatível, apresentandose em sua maioria adultos jovens, do sexo masculino e solteiros 2014-12-17T14:16:22Z 2009-03-31 2014-12-17T14:16:22Z 2008-09-23 masterThesis SANTIAGO, Edna de Farias. Alcoolemia em vítimas fatais de acidentes de trânsito no Rio Grande do Norte empregando cromatografia em fase gasosa - head space. 2008. 93 f. Dissertação (Mestrado em Bioanálises e Medicamentos) - Universidade Federal do Rio Grande do Norte, Natal, 2008. https://repositorio.ufrn.br/jspui/handle/123456789/13440 por Acesso Aberto application/pdf application/pdf Universidade Federal do Rio Grande do Norte BR UFRN Programa de Pós-Graduação em Ciências Farmacêuticas Bioanálises e Medicamentos |