Análise do efeito de polimorfismos não-sinônimos em genes de reparo de DNA da via BER na resposta inflamatória da meningite
In vitro and in animal models, APE1, OGG1, and PARP-1 have been proposed as being involved with inflammatory response. In this work, we have investigated if the SNPs APE1 Asn148Glu, OGG1 Ser326Cys, and PARP-1 Val762Ala are associated to meningitis and also developed a system to enable the functional...
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| フォーマット: | doctoralThesis |
| 言語: | por |
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Universidade Federal do Rio Grande do Norte
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| オンライン･アクセス: | https://repositorio.ufrn.br/jspui/handle/123456789/12651 |
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