Análise do efeito de polimorfismos não-sinônimos em genes de reparo de DNA da via BER na resposta inflamatória da meningite

In vitro and in animal models, APE1, OGG1, and PARP-1 have been proposed as being involved with inflammatory response. In this work, we have investigated if the SNPs APE1 Asn148Glu, OGG1 Ser326Cys, and PARP-1 Val762Ala are associated to meningitis and also developed a system to enable the functional...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Silva, Thayse Azevedo da
Awduron Eraill: Lima, Lucymara Fassarela Agnez
Fformat: doctoralThesis
Iaith:por
Cyhoeddwyd: Universidade Federal do Rio Grande do Norte
Pynciau:
Mynediad Ar-lein:https://repositorio.ufrn.br/jspui/handle/123456789/12651
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!