Pseudomembranous Colitis – a review

Pseudomembranous colitis is a disease caused by Clostridium difficile that predominantly affects the lower gastrointestinal tract. Its main risk factors are antibiotic use, advanced age and hospitalization. We used the keywords Pseudomembranous colitis, Clostridium difficile, Antibiotics, Pseudomemb...

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Principais autores: Carvalho, Aline Vasconcelos, Medeiros-Júnior, Arnaldo Costa de, Chaves, Bárbara Monitchelly Fernandes, Xavier, Clara Rafael Silva, Rêgo, Amália Cíntia Meneses do, Araújo-Filho, Irami, Medeiros, Aldo da Cunha
Formato: Online
Idioma:por
Publicado em: FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE, BRAZIL
Endereço do item:https://periodicos.ufrn.br/jscr/article/view/5495
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spelling oai:periodicos.ufrn.br:article-54952019-06-05T23:31:18Z Pseudomembranous Colitis – a review Carvalho, Aline Vasconcelos Medeiros-Júnior, Arnaldo Costa de Chaves, Bárbara Monitchelly Fernandes Xavier, Clara Rafael Silva Rêgo, Amália Cíntia Meneses do Araújo-Filho, Irami Medeiros, Aldo da Cunha Pseudomebranous colitis Clostridium difficile Antibiotics Pseudomembranes Fulminant colitis Pseudomembranous colitis is a disease caused by Clostridium difficile that predominantly affects the lower gastrointestinal tract. Its main risk factors are antibiotic use, advanced age and hospitalization. We used the keywords Pseudomembranous colitis, Clostridium difficile, Antibiotics, Pseudomembranous, Fulminant colitis, and the search was performed in PubMed, Virtual Health Library-Brazil, Embase and Scopus. Pathogenesis is not fully understood. The most frequent clinical presentation occurs with typical symptoms. Laboratory identification of C. difficile toxin in the stool sample and / or viewing pseudomembranes in endoscopy are essential for a definitive diagnosis. The initial drug treatment is available, however many complications can occur, and surgery may be performed for the most severe cases. The current available technologies are not yet able to resolve all cases. So many other challenges must be overcome regarding the treatment and its pathogenesis, especially in refractory and recurrent disease. FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE, BRAZIL 2014-07-11 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://periodicos.ufrn.br/jscr/article/view/5495 JOURNAL OF SURGICAL AND CLINICAL RESEARCH; Vol. 4 No. 2 (2013); 63-70 JOURNAL OF SURGICAL AND CLINICAL RESEARCH; v. 4 n. 2 (2013); 63-70 2179-7889 por https://periodicos.ufrn.br/jscr/article/view/5495/4481 Copyright (c) 2014 JOURNAL OF SURGICAL AND CLINICAL RESEARCH
institution Periódicos UFRN
collection Portal de Pediódicos Eletrônicos da UFRN
language por
format Online
author Carvalho, Aline Vasconcelos
Medeiros-Júnior, Arnaldo Costa de
Chaves, Bárbara Monitchelly Fernandes
Xavier, Clara Rafael Silva
Rêgo, Amália Cíntia Meneses do
Araújo-Filho, Irami
Medeiros, Aldo da Cunha
spellingShingle Carvalho, Aline Vasconcelos
Medeiros-Júnior, Arnaldo Costa de
Chaves, Bárbara Monitchelly Fernandes
Xavier, Clara Rafael Silva
Rêgo, Amália Cíntia Meneses do
Araújo-Filho, Irami
Medeiros, Aldo da Cunha
Pseudomembranous Colitis – a review
author_facet Carvalho, Aline Vasconcelos
Medeiros-Júnior, Arnaldo Costa de
Chaves, Bárbara Monitchelly Fernandes
Xavier, Clara Rafael Silva
Rêgo, Amália Cíntia Meneses do
Araújo-Filho, Irami
Medeiros, Aldo da Cunha
author_sort Carvalho, Aline Vasconcelos
title Pseudomembranous Colitis – a review
title_short Pseudomembranous Colitis – a review
title_full Pseudomembranous Colitis – a review
title_fullStr Pseudomembranous Colitis – a review
title_full_unstemmed Pseudomembranous Colitis – a review
title_sort pseudomembranous colitis – a review
description Pseudomembranous colitis is a disease caused by Clostridium difficile that predominantly affects the lower gastrointestinal tract. Its main risk factors are antibiotic use, advanced age and hospitalization. We used the keywords Pseudomembranous colitis, Clostridium difficile, Antibiotics, Pseudomembranous, Fulminant colitis, and the search was performed in PubMed, Virtual Health Library-Brazil, Embase and Scopus. Pathogenesis is not fully understood. The most frequent clinical presentation occurs with typical symptoms. Laboratory identification of C. difficile toxin in the stool sample and / or viewing pseudomembranes in endoscopy are essential for a definitive diagnosis. The initial drug treatment is available, however many complications can occur, and surgery may be performed for the most severe cases. The current available technologies are not yet able to resolve all cases. So many other challenges must be overcome regarding the treatment and its pathogenesis, especially in refractory and recurrent disease.
publisher FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE, BRAZIL
publishDate 2014
url https://periodicos.ufrn.br/jscr/article/view/5495
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