THE EFFECT OF TURMERIC ON ULCERATIVE COLITIS: A PERSPECTIVE: The Effect of Turmeric on Ulcerative Colitis

Ulcerative colitis (UC) is a chronic inflammatory bowel disease with limited treatment options and potential side effects. Curcumin, derived from Curcuma longa, has demonstrated anti-inflammatory and immunomodulatory properties, making it a potential therapeutic choice for UC. This review summarizes...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Principais autores: Araujo-Filho, Irami, Moraes da Cunha, Franciara Leticea, Meneses do Rêgo, Amália Cinthia
Formato: Online
Idioma:eng
Publicado em: FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE, BRAZIL
Endereço do item:https://periodicos.ufrn.br/jscr/article/view/33079
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
id oai:periodicos.ufrn.br:article-33079
record_format ojs
spelling oai:periodicos.ufrn.br:article-330792023-07-17T16:22:22Z THE EFFECT OF TURMERIC ON ULCERATIVE COLITIS: A PERSPECTIVE: The Effect of Turmeric on Ulcerative Colitis Araujo-Filho, Irami Moraes da Cunha, Franciara Leticea Meneses do Rêgo, Amália Cinthia ulcerative colitis curcumin anti-inflammatory immunomodulatory complementary therapy Ulcerative colitis (UC) is a chronic inflammatory bowel disease with limited treatment options and potential side effects. Curcumin, derived from Curcuma longa, has demonstrated anti-inflammatory and immunomodulatory properties, making it a potential therapeutic choice for UC. This review summarizes the literature on the impact of curcumin on UC management and its mechanisms of action. The included studies demonstrated that curcumin supplementation can lead to clinical remission, improved endoscopic findings, and reduced inflammatory markers in patients with UC. Curcumin's ability to target multiple pathways involved in the pathogenesis of UC makes it a promising adjunctive therapy. However, there are limitations due to the various study designs, curcumin dosages, and formulations. More well-designed clinical trials are needed to establish optimal dosing and evaluate long-term safety and efficacy. In conclusion, curcumin shows potential as a complementary therapy for UC due to its anti-inflammatory properties. Although more research is needed, current evidence suggests that curcumin supplementation may offer clinical benefits in managing UC. Future studies should standardize formulations, optimize dosages, and investigate long-term effects. Ulcerative colitis (UC) is a chronic inflammatory bowel disease with limited treatment options and potential side effects. Curcumin, derived from Curcuma longa, has demonstrated anti-inflammatory and immunomodulatory properties, making it a potential therapeutic choice for UC. This review summarizes the literature on the impact of curcumin on UC management and its mechanisms of action. The included studies demonstrated that curcumin supplementation can lead to clinical remission, improved endoscopic findings, and reduced inflammatory markers in patients with UC. Curcumin's ability to target multiple pathways involved in the pathogenesis of UC makes it a promising adjunctive therapy. However, there are limitations due to the various study designs, curcumin dosages, and formulations. More well-designed clinical trials are needed to establish optimal dosing and evaluate long-term safety and efficacy. In conclusion, curcumin shows potential as a complementary therapy for UC due to its anti-inflammatory properties. Although more research is needed, current evidence suggests that curcumin supplementation may offer clinical benefits in managing UC. Future studies should standardize formulations, optimize dosages, and investigate long-term effects. FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE, BRAZIL 2023-07-17 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://periodicos.ufrn.br/jscr/article/view/33079 JOURNAL OF SURGICAL AND CLINICAL RESEARCH; Vol. 14 No. 1 (2023); 73-82 JOURNAL OF SURGICAL AND CLINICAL RESEARCH; v. 14 n. 1 (2023); 73-82 2179-7889 eng https://periodicos.ufrn.br/jscr/article/view/33079/17220 Copyright (c) 2023 JOURNAL OF SURGICAL AND CLINICAL RESEARCH http://creativecommons.org/licenses/by-nc-sa/4.0
institution Periódicos UFRN
collection Portal de Pediódicos Eletrônicos da UFRN
language eng
format Online
author Araujo-Filho, Irami
Moraes da Cunha, Franciara Leticea
Meneses do Rêgo, Amália Cinthia
spellingShingle Araujo-Filho, Irami
Moraes da Cunha, Franciara Leticea
Meneses do Rêgo, Amália Cinthia
THE EFFECT OF TURMERIC ON ULCERATIVE COLITIS: A PERSPECTIVE: The Effect of Turmeric on Ulcerative Colitis
author_facet Araujo-Filho, Irami
Moraes da Cunha, Franciara Leticea
Meneses do Rêgo, Amália Cinthia
author_sort Araujo-Filho, Irami
title THE EFFECT OF TURMERIC ON ULCERATIVE COLITIS: A PERSPECTIVE: The Effect of Turmeric on Ulcerative Colitis
title_short THE EFFECT OF TURMERIC ON ULCERATIVE COLITIS: A PERSPECTIVE: The Effect of Turmeric on Ulcerative Colitis
title_full THE EFFECT OF TURMERIC ON ULCERATIVE COLITIS: A PERSPECTIVE: The Effect of Turmeric on Ulcerative Colitis
title_fullStr THE EFFECT OF TURMERIC ON ULCERATIVE COLITIS: A PERSPECTIVE: The Effect of Turmeric on Ulcerative Colitis
title_full_unstemmed THE EFFECT OF TURMERIC ON ULCERATIVE COLITIS: A PERSPECTIVE: The Effect of Turmeric on Ulcerative Colitis
title_sort effect of turmeric on ulcerative colitis: a perspective: the effect of turmeric on ulcerative colitis
description Ulcerative colitis (UC) is a chronic inflammatory bowel disease with limited treatment options and potential side effects. Curcumin, derived from Curcuma longa, has demonstrated anti-inflammatory and immunomodulatory properties, making it a potential therapeutic choice for UC. This review summarizes the literature on the impact of curcumin on UC management and its mechanisms of action. The included studies demonstrated that curcumin supplementation can lead to clinical remission, improved endoscopic findings, and reduced inflammatory markers in patients with UC. Curcumin's ability to target multiple pathways involved in the pathogenesis of UC makes it a promising adjunctive therapy. However, there are limitations due to the various study designs, curcumin dosages, and formulations. More well-designed clinical trials are needed to establish optimal dosing and evaluate long-term safety and efficacy. In conclusion, curcumin shows potential as a complementary therapy for UC due to its anti-inflammatory properties. Although more research is needed, current evidence suggests that curcumin supplementation may offer clinical benefits in managing UC. Future studies should standardize formulations, optimize dosages, and investigate long-term effects.
publisher FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE, BRAZIL
publishDate 2023
url https://periodicos.ufrn.br/jscr/article/view/33079
work_keys_str_mv AT araujofilhoirami theeffectofturmericonulcerativecolitisaperspectivetheeffectofturmericonulcerativecolitis
AT moraesdacunhafranciaraleticea theeffectofturmericonulcerativecolitisaperspectivetheeffectofturmericonulcerativecolitis
AT menesesdoregoamaliacinthia theeffectofturmericonulcerativecolitisaperspectivetheeffectofturmericonulcerativecolitis
AT araujofilhoirami effectofturmericonulcerativecolitisaperspectivetheeffectofturmericonulcerativecolitis
AT moraesdacunhafranciaraleticea effectofturmericonulcerativecolitisaperspectivetheeffectofturmericonulcerativecolitis
AT menesesdoregoamaliacinthia effectofturmericonulcerativecolitisaperspectivetheeffectofturmericonulcerativecolitis
_version_ 1771948239252094976

Registros relacionados