Attenuation of lung injury using simvastatin in a rat sepsis model

Purpose: Considering that statins have pleiotrophic effects, we hypothesized that vimvastatin therapy could help in the setting of sepsis and lung injury. The aim of this study was to address the effect of simvastatin pretreatment on lung injury in rats with abdominal sepsis. Methods: Thirty male Wi...

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Autori principali: Medeiros, Vítor Brasil, Azevedo, Ítalo Medeiros de, Rego, Amália Cínthia Meneses, Araújo-Filho, Irami, Carvalho, Marília Daniela Ferreira, Medeiros, Aldo Cunha
Natura: Online
Lingua:por
Pubblicazione: FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE, BRAZIL
Accesso online:https://periodicos.ufrn.br/jscr/article/view/3141
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