Analysis of possible drug interactions in covid-19 treatment associated with breast cancer oncology therapy

In December 2019, an outbreak began in the city of Wuhan (China) of a new strain of the coronavirus family, called SARS-COV-2. The epidemiological situation in the world was changed by the unexpected arrival of the SARS-COV-2 virus, bringing many collections to health, mainly within the risk group c...

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Principais autores: Lopes Cavalcante, Mirian, Corrêa Melo, Maria Madalena, Monteiro Carvalho, Alessandro, Oliveira Santos, Delzianny, Queiroz Cavalcante Carvalho, Lisança, Pinheiro Luz , Luis Carlos, da Silva, Regina Célia, de Sousa Rocha Barros, Lissandra, de Almeida da Costa, Mateus Henrique, Allende Costa de Souza Pereira, Natatscha, Rangel Santos, Carina, Vilas Boas Baena Castillo, Andressa, do Nascimento, Samaritana Barros, de Jesus Costa, Sufia, Oliveira Linhares, Byatriz
Formato: Online
Idioma:por
Publicado em: Max Leandro de Araújo Brito
Endereço do item:https://periodicos.ufrn.br/casoseconsultoria/article/view/e27858
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Resumo:In December 2019, an outbreak began in the city of Wuhan (China) of a new strain of the coronavirus family, called SARS-COV-2. The epidemiological situation in the world was changed by the unexpected arrival of the SARS-COV-2 virus, bringing many collections to health, mainly within the risk group classification. Faced with the new epidemiological situation, the scientific community sought ways to control the new disease. Breast cancer is the cancer that most affects Brazilian women, considering the importance of this risk group and research work related to the safety of treatment for COVID-19 in infected patients who have breast cancer, this work gathered information about possible drug interactions and inherent risks, thus becoming a tool that will increase the safety of cancer patients. It is characterized as a documentary research, with a quantitative, retrospective, analytical-discursive approach that uses a Drugs® database to obtain cross-referenced information from databases with other drugs. Research is known that some of the drugs used by the population in the treatment or prevention of COVID-19 have several drug interactions with drugs used to treat breast cancer, with methotrexate and tamoxifen being the ones with the highest number interactions, some of which are very serious. Thus, if the breast cancer patient is using some medications, the cost-effectiveness needs to be analyzed by the physician, as well as the patient needs to be monitored during use, so that the cancer treatment is not harmed.

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