Matrix Metalloproteinases in Tissue Remodelling and Inflammation

Matrix metalloproteinases (MMPs) are proteolytic enzymes believed to be involved in many physiological and pathological processes associated with inflammatory reactions. MMP synthesis and functions are regulated by three major mechanisms including transcriptional activation, post-transcriptional pro...

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Principais autores: Lagente, Vincent., Boichot, Elisabeth., SpringerLink (Online service)
Formato: Digital
Publicado em:
Assuntos:
Patologia.
Infecção
Imunologia clínica.
Toxicologia.
Pneumologia.
Citologia.
Biomedicina.
Endereço do item:http://dx.doi.org/10.1007/978-3-7643-8585-9
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spelling oai:localhost:123456789-2126032023-07-17T15:09:21Z Matrix Metalloproteinases in Tissue Remodelling and Inflammation Lagente, Vincent. Boichot, Elisabeth. SpringerLink (Online service) Patologia. Infecção Imunologia clínica. Toxicologia. Pneumologia. Citologia. Biomedicina. Matrix metalloproteinases (MMPs) are proteolytic enzymes believed to be involved in many physiological and pathological processes associated with inflammatory reactions. MMP synthesis and functions are regulated by three major mechanisms including transcriptional activation, post-transcriptional processing, and control of activity by tissue inhibitors of metalloproteinases (TIMPs). Many cell types have been identified as producers of MMPs and TIMPs in a context of inflammatory processes. MMPs are involved in numerous inflammatory diseases, including respiratory, cardiovascular and central nervous system pathologies. This volume presents new advances in the involvement of MMPs in various diseases associated with inflammatory processes. Moreover, the recent development of selective and non selective inhibitors of MMPs provides new insights in the relationship between activation of inflammatory cells and tissue remodelling and advises new therapeutic possibilities for the treatment of inflammatory diseases. 0 2022-10-11T17:43:10Z 2022-10-11T17:43:10Z 2008. Digital 616 M433 9783764385859 198692 http://dx.doi.org/10.1007/978-3-7643-8585-9 http://dx.doi.org/10.1007/978-3-7643-8585-9
institution Acervo SISBI
collection SIGAA
topic Patologia.
Infecção
Imunologia clínica.
Toxicologia.
Pneumologia.
Citologia.
Biomedicina.
spellingShingle Patologia.
Infecção
Imunologia clínica.
Toxicologia.
Pneumologia.
Citologia.
Biomedicina.
Lagente, Vincent.
Boichot, Elisabeth.
SpringerLink (Online service)
Matrix Metalloproteinases in Tissue Remodelling and Inflammation
description Matrix metalloproteinases (MMPs) are proteolytic enzymes believed to be involved in many physiological and pathological processes associated with inflammatory reactions. MMP synthesis and functions are regulated by three major mechanisms including transcriptional activation, post-transcriptional processing, and control of activity by tissue inhibitors of metalloproteinases (TIMPs). Many cell types have been identified as producers of MMPs and TIMPs in a context of inflammatory processes. MMPs are involved in numerous inflammatory diseases, including respiratory, cardiovascular and central nervous system pathologies. This volume presents new advances in the involvement of MMPs in various diseases associated with inflammatory processes. Moreover, the recent development of selective and non selective inhibitors of MMPs provides new insights in the relationship between activation of inflammatory cells and tissue remodelling and advises new therapeutic possibilities for the treatment of inflammatory diseases.
format Digital
author Lagente, Vincent.
Boichot, Elisabeth.
SpringerLink (Online service)
author_facet Lagente, Vincent.
Boichot, Elisabeth.
SpringerLink (Online service)
author_sort Lagente, Vincent.
title Matrix Metalloproteinases in Tissue Remodelling and Inflammation
title_short Matrix Metalloproteinases in Tissue Remodelling and Inflammation
title_full Matrix Metalloproteinases in Tissue Remodelling and Inflammation
title_fullStr Matrix Metalloproteinases in Tissue Remodelling and Inflammation
title_full_unstemmed Matrix Metalloproteinases in Tissue Remodelling and Inflammation
title_sort matrix metalloproteinases in tissue remodelling and inflammation
publishDate 2022
url http://dx.doi.org/10.1007/978-3-7643-8585-9
work_keys_str_mv AT lagentevincent matrixmetalloproteinasesintissueremodellingandinflammation
AT boichotelisabeth matrixmetalloproteinasesintissueremodellingandinflammation
AT springerlinkonlineservice matrixmetalloproteinasesintissueremodellingandinflammation
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